Alstiphyllanines A-D, Indole Alkaloids from Alstonia macrophylla

被引：24

作者：

Hirasawa, Yusuke ^{[1
]}

Arai, Hiroko ^{[1
]}

Zaima, Kazumasa ^{[1
]}

Oktarina, Rice ^{[2
]}

Rahman, Abdul ^{[2
]}

Ekasari, Wiwied ^{[2
]}

Widyawaruyanti, Aty ^{[2
]}

Indrayanto, Gunawan ^{[2
]}

Zaini, Noor Cholies ^{[2
]}

Morita, Hiroshi ^{[1
]}

机构：

[1] Hoshi Univ, Fac Pharmaceut Sci, Shinagawa Ku, Tokyo 1428501, Japan

[2] Airlangga Univ, Fac Pharm, Jalan Dharmawangsa Dalam 60286, Surabaya, Indonesia

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 02期

关键词：

KOPSIA-FLAVIDA BLUME; IN-VITRO; SCHOLARIS; DRUGS; PARASITES; LEAVES; PLANTS;

D O I：

10.1021/np8007107

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new alkaloids, alstiphyllanines A-D (1-4), were isolated from Alstonia macrophylla, and their structures were determined by MS and 2D NMR analyses. Alkaloids 1-4 showed moderate antiplasmodial activity against Plasmodium falciparum and vasorelaxant activity against phenylephrine-induced contraction of isolated rat aorta.

引用

页码：304 / 307

页数：4

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