Localization of D-1 dopamine receptors in the chicken retina

Purpose: The localization of dopamine D-1 receptors (DIR) in the chicken retina was examined using an anti-human DIR monoclonal antibody and PAP techniques. Results: A clear band of staining was seen in the outer plexiform layer; as well as cellular staining in the outer-most part of the inner nuclear layer; probably in a subset of horizontal cells. Many different amacrine cell bodies were labelled in the inner one-third of the inner nuclear layer. There was also extensive staining in the inner plexiform layer which showed some striation. Occasional labelled ganglion cells were also detected. Conclusion: Localization of D1-dopamine receptors has been shown in the chicken retina.