Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora

被引:18
|
作者
Starlin, Thangarajan [1 ]
Prabha, Poochi Saravana [1 ]
Thayakumar, Basanth Kumar Allen [2 ]
Gopalakrishnan, Velliyur Kanniappan [1 ]
机构
[1] Karpagam Acad Higher Educ, Dept Biochem & Bioinformat, Coimbatore 64102, Tamil Nadu, India
[2] Mitra RxDx Inc, Dept Canc Biol, Woburn, MA 01801 USA
关键词
Tylophora pauciflora; ethanolic extract; GC-MS analysis; bioactive compounds; CHROMATOGRAPHY;
D O I
10.6026/97320630015425
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant activity, anti-inflammatory activity and anti cancer activity. There is no GC-MS analysis reported on this plant. Thus, the present study is aimed to identify the present of phyto-chemical compounds from ethanolic extract of Tylophora pauciflora using GC-MS analysis. Results, the extract possess totally 14 bioactive compounds among that natural compound of n-hexadecanoic acid has highest % peak area and it have the variety of biological activities such as; anti-oxidant, 5-alpha-reductase-inhibitor, anti-fibrinolytic, hemolytic, antimicrobial activity, hypo-cholesterolemic, nematicide, pesticide, anti-androgenic flavor and hemolytic. It is concluded that the ethanolic extract of Tylophora pauciflora have biologically active compounds. In future by isolating and identifying, these compounds can be considered to treat the human disorders.
引用
收藏
页码:425 / 429
页数:5
相关论文
共 50 条
  • [1] Phytochemical Screening and GC-MS Studies on the Ethanolic Extract of Cayratia pedata
    Stanley, A. Leo
    Ramani, V. Alex
    Ramachandran, A.
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND PHYTOPHARMACOLOGICAL RESEARCH, 2011, 1 (03): : 112 - 116
  • [2] Phytochemical Screening and GC-MS Studies on the Ethanolic Extract of Turnera Ulmifolia L
    Kalimuthu, K.
    Prabakaran, R.
    Preetha, V.
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND PHYTOPHARMACOLOGICAL RESEARCH, 2014, 4 (03): : 179 - 181
  • [3] LC-MS and GC-MS Profiling of Different Fractions of Ficus platyphylla Stem Bark Ethanolic Extract
    Hassan, Madinat
    Bala, Sunday Zeal
    Bashir, Musa
    Waziri, Peter Maitalata
    Musa Adam, Ramlatu
    Umar, Muhammad Abdullahi
    Kini, Priscilla
    [J]. JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY, 2022, 2022
  • [4] PHYTOCHEMICAL ANALYSIS OF ETHANOLIC EXTRACT OF PROSOPIS CINERARIA PODS BY GC-MS
    Sharma, Garima
    Devki
    Vyas, Ruchi
    Sisodia, Rashmi
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2021, 12 (01): : 418 - 431
  • [5] Identification of the chemical constituents in Cullen corylifolium ethanolic extract by LC-MS/MS and GC-MS
    Wang, Hongzheng
    Chen, Keyu
    Xue, Rui
    Turghun, Chimengul
    Han, Bo
    [J]. NATURAL PRODUCT RESEARCH, 2023, 37 (08) : 1392 - 1396
  • [6] Phytochemical Profiling, GC-MS Analysis and α-Amylase Inhibitory Potential of Ethanolic Extract of Cocos nucifera Linn. Endocarp
    Singla, Rajeev Kumar
    Dubey, Ashok Kumar
    [J]. ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2019, 19 (04) : 419 - 442
  • [7] GC-MS analysis of ethanolic extract of propolis from Jhajjar district in Haryana, India
    Sharma, S.
    Rana, A.
    Khakhlary, D.
    [J]. JOURNAL OF ENVIRONMENTAL BIOLOGY, 2024, 45 (03): : 253 - 258
  • [8] Phytocompound profiling and GC-MS analysis of Lantana camara leaf extract
    He, Aimin
    Chadha, Shivika
    Saruchi
    Kumar, Vaneet
    [J]. JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2024, 101 (11)
  • [9] PHYTOCHEMICAL SCREENING AND GC-MS STUDIES OF THE METHANOLIC EXTRACT OF TRIDAX PROCUMBENS
    Kushwaha, Pankaj
    Yadav, Shiv Shankar
    Singh, Vigyan
    Dwivedi, L. K.
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2019, 10 (05): : 2492 - 2496
  • [10] Phytochemical Screening and GC-MS Analysis of Flower Extract of Dillenia indica
    Gupta, Ashish
    Kumari, Nishi
    Tiwari, Ida
    [J]. BIOSCIENCE BIOTECHNOLOGY RESEARCH COMMUNICATIONS, 2020, 13 (02): : 833 - 841