Recurrent life-threatening reactions to platelet transfusion in an aplastic anaemia patient with a paroxysmal nocturnal haemoglobinuria clone

被引：0
|
作者：
Mohamed, M. [1 ,2 ]
Bates, G. [1 ]
Richardson, D. [1 ]
Burrows, L. [3 ]
机构：
[1] Launceston Gen Hosp, Haematol Dept, Launceston, Tas 7250, Australia
[2] Univ Tasmania, Launceston Clin Sch, Launceston, Tas 7250, Australia
[3] Australian Red Cross Blood Serv, Med Serv, Melbourne, Vic, Australia
来源：
INTERNAL MEDICINE JOURNAL | 2014年 / 44卷 / 09期
关键词：
PNH; platelet transfusion; recurrent reaction; washed platelet; aplastic anaemia; RED-CELL TRANSFUSIONS; IGA;
D O I：
10.1111/imj.12528
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 60-year-old woman was diagnosed with non-severe aplastic anaemia when she presented with anaemia and thrombocytopenia. She developed recurrent life-threatening hypotensive reactions during transfusion of leukodepleted platelet concentrates, and washed platelet concentrates prevented the development of such reactions subsequently. A paroxysmal nocturnal haemoglobinuria clone was detected on investigating for aplastic anaemia, which has been speculated to play a role in the recurrent hypotensive reactions.
引用
收藏
页码：925 / 927
页数：3
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