Ovarian enzyme activities in women with polycystic ovary syndrome

被引：28
|
作者：
Magoffin, Denis A. [1 ]
机构：
[1] Univ Calif Los Angeles, David Geffen Sch Med, Cedars Sinai Burns & Allen Res Inst, Dept Obstet & Gynecol, Los Angeles, CA 90048 USA
来源：
FERTILITY AND STERILITY | 2006年 / 86卷
关键词：
ovary; androgen production; PCOS; steroidogenesis;
D O I：
10.1016/j.fertnstert.2006.03.015
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Studies using primary ovarian tissue and cultured human theca and granulosa cells have shown that steroidogenic enzyme,activities are up-regulated in theca cells in polycystic ovary syndrome (PCOS). Although granulosa cells in arrested follicles in PCOS fail to express significant amounts of aromatase, there is an overexpression of 5 alpha-reductase activity and premature expression of cholesterol side-chain cleavage cytochrome P450.
引用
收藏
页码：S9 / S11
页数：3
相关论文
共 50 条
  • [1] Biomarkers of Ovarian Reserve in Women with Polycystic Ovary Syndrome
    Huddleston, Heather Gibson
    [J]. SEMINARS IN REPRODUCTIVE MEDICINE, 2013, 31 (06) : 452 - 461
  • [2] Outcome of Ovarian Drilling in Women with Polycystic Ovary Syndrome
    Yanamandra, Niraj K.
    Gundabattula, Sirisha Rao
    [J]. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2015, 9 (02) : QC1 - QC3
  • [3] Ovarian drilling in infertile women with polycystic ovary syndrome
    Rose, BI
    [J]. JOURNAL OF THE AMERICAN ASSOCIATION OF GYNECOLOGIC LAPAROSCOPISTS, 1997, 3 (03): : 461 - 468
  • [4] Systemic and ovarian inflammation in women with polycystic ovary syndrome
    Zhai, Yi
    Pang, Yanli
    [J]. JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2022, 151
  • [5] Polycystic ovarian morphology in Thai women of reproductive age with polycystic ovary syndrome
    Wongwananuruk, Thanyarat
    Chantrapanichkul, Panicha
    Unalome, Vichuta
    Indhavivadhana, Suchada
    Rattanachaiyanont, Manee
    Techatraisak, Kitirat
    Angsuwathana, Surasak
    Silprasit, Kittayaporn
    [J]. ASIAN BIOMEDICINE, 2020, 14 (06) : 271 - 277
  • [6] Ovarian surgery for symptom relief in women with polycystic ovary syndrome
    Lepine, Sam
    Jo, Junyoung
    Metwally, Mostafa
    Cheong, Ying C.
    [J]. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2017, (11):
  • [7] Relationship of Biological Markers of Body Fat Distribution and Corticosteroidogenic Enzyme Activities in Women with Polycystic Ovary Syndrome
    de Medeiros, Sebastiao Freitas
    Souto de Medeiros, Matheus Antonio
    Barbosa, Bruna Barcelo
    Winck Yamamoto, Marcia Marly
    [J]. HORMONE AND METABOLIC RESEARCH, 2019, 51 (10) : 639 - 648
  • [8] Polycystic ovarian morphology in normal women does not predict the development of polycystic ovary syndrome
    Murphy, M. K.
    Hall, J. E.
    Adams, J. M.
    Lee, H.
    Welt, C. K.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 91 (10): : 3878 - 3884
  • [9] Association between polycystic ovarian morphology and insulin resistance in women with polycystic ovary syndrome
    Lee, Jeong Eun
    Park, Yubin
    Lee, Jisoo
    Chun, Sungwook
    [J]. CLINICAL AND EXPERIMENTAL REPRODUCTIVE MEDICINE-CERM, 2023, 50 (02): : 117 - 122
  • [10] Ovarian failure and polycystic ovary syndrome
    Petrikova, Jana
    Lazurova, Ivica
    [J]. AUTOIMMUNITY REVIEWS, 2012, 11 (6-7) : A471 - A478
12345