Initial genome wide parametric genetic linkage analysis of schizophrenia and schizophrenia spectrum disorders finds lod scores above 3.00 on four chromosomes at 1Q22-23, 5Q22-35, 8P21-23 and 11Q14-24. a further lod above 3.00 at 4Q21-31 was found within a single family.

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Gurling, HMD
Kalsi, G
Blaveri, E
McQuillin, A
Read, T
Murphy, P
Butler, R
Brynjolfsson, J
Sigmundsson, T
Petursson, H
Curtis, D
机构
[1] UCL Royal Free & Univ Coll, Sch Med, Mol Psychiat Lab, Windeyer Inst Med Sci,Dept Psychiat & Behav Sci, London W1P 6DB, England
[2] Univ Iceland, Gen Hosp, Dept Psychiat, Reykjavik, Iceland
[3] St Bartholomews & Royal London Sch Med & Dent, Joint Acad Dept Psychol Med, London E1 1BB, England
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Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
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页码:S4 / S4
页数:1
相关论文
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  • [1] Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23
    Gurling, HMD
    Kalsi, G
    Brynjolfson, J
    Sigmundsson, T
    Sherrington, R
    Mankoo, BS
    Read, T
    Murphy, P
    Blaveri, E
    McQuillin, A
    Petursson, H
    Curtis, D
    AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 68 (03) : 661 - 673