A specific problem of the therapy of neurodegenerative disorders is mental symptoms, which significantly worsen the social adaptation of patients and further prognosis, require additional therapy with antipsychotics, often giving various side effects. For the period from 2019 to 2021, 51 clinical cases of various nosological forms of dementia were analyzed in the neurodegenerative center Yakut scientific center. Alzheimer's disease was most often diagnosed - 29 cases (56.8%), patients with frontotemporal dementia were most often admitted in second place - 9 people (17.6%), dementia with Levi's corpuscles (7.8%) and vascular dementia (7.8%) were most often diagnosed in third place. The average overall score on the Moca scale was 10.08+5.9 points, which corresponds to severe cognitive impairment. The difference in the age of manifestation in different ethnic groups of patients was established, as well as clinical and psychopathological features of patients with various nosological forms of dementia, taking into account ethnicity, as well as features of corrective therapy. Of the non-cognitive neuropsychic disorders, the symptom of agitation and aggression was most often detected.