Direct, real-time PCR (MethyLight) assay for methylation of O6-methylguanine-DNA methyltransferase promoter in glioma

被引：2
|
作者：
Chen Gong [1 ]
Wu Xing [1 ]
Yao Yu [1 ]
Zhou Liang-fu [1 ]
Mao Ying [1 ]
机构：
[1] Fudan Univ, Huashan Hosp, Dept Neurosurg, Shanghai 200040, Peoples R China
来源：
CHINESE MEDICAL JOURNAL | 2009年 / 122卷 / 11期
关键词：
O6-methylguanine-DNA-methyltransferase; real-time PCR; methylation-specific PCR; glioma; drug resistance; O-6-METHYLGUANINE DNA METHYLTRANSFERASE; GENE; MGMT; TEMOZOLOMIDE; GLIOBLASTOMA; HYPERMETHYLATION; INACTIVATION;
D O I：
10.3760/cma.j.issn.0366-6999.2009.11.019
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：1342 / 1345
页数：4
相关论文
共 50 条
  • [1] Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma
    Vlassenbroeck, Ilse
    Califice, Stephane
    Diserens, Annie-Claire
    Migliavacca, Eugenia
    Straub, Josef
    Di Stefano, Ivano
    Moreau, Fabrice
    Hamou, Marie-France
    Renard, Isabelle
    Delorenzi, Mauro
    Flamion, Bruno
    DiGuiseppi, James
    Bierau, Katja
    Hegi, Monika E.
    [J]. JOURNAL OF MOLECULAR DIAGNOSTICS, 2008, 10 (04): : 332 - 337
  • [2] O6-Methylguanine-DNA Methyltransferase Gene Promoter Methylation Detection in Glioma Tumors by a Novel Fluorescence Polarization Assay
    Wu, Zhongliang
    Zhang, Ju
    Cheng, Hong
    Liang, Ping
    Guo, Yanhai
    Yan, Zhen
    Zhao, Jinrong
    [J]. DIAGNOSTIC MOLECULAR PATHOLOGY, 2010, 19 (04) : 232 - 235
  • [3] Glioblastoma Recurrence and the Role of O6-Methylguanine-DNA Methyltransferase Promoter Methylation
    Storey, Katie
    Leder, Kevin
    Hawkins-Daarud, Andrea
    Swanson, Kristin
    Ahmed, Atique U.
    Rockne, Russell C.
    Foo, Jasmine
    [J]. JCO CLINICAL CANCER INFORMATICS, 2019, 3 : 1 - 12
  • [4] The Correlation between Promoter Methylation Status and the Expression Level of O6-Methylguanine-DNA Methyltransferase in Recurrent Glioma
    Suzuki, Tomohide
    Nakada, Mitsutoshi
    Yoshida, Yuya
    Nambu, Emi
    Furuyama, Natsuki
    Kita, Daisuke
    Hayashi, Yutaka
    Hayashi, Yasuhiko
    Hamada, Jun-ichiro
    [J]. JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2011, 41 (02) : 190 - 196
  • [5] PROGNOSTIC IMPACT OF O6-METHYLGUANINE-DNA METHYLTRANSFERASE (MGMT) PROMOTER METHYLATION IN MEDULLOBLASTOMA
    Kondo, Akihide
    Kurimoto, Tomoko
    Sakaguchi, Sachi
    Arai, Hajime
    [J]. NEURO-ONCOLOGY, 2015, 17 : 21 - 21
  • [6] O6-methylguanine-DNA methyltransferase activity and promoter methylation status in pediatric rhabdomyosarcoma
    Yeager, ND
    Dolan, ME
    Gastier, JM
    Gross, TG
    Delaney, S
    Frick, J
    Ruymann, FB
    Ewesuedo, R
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2003, 25 (12) : 941 - 947
  • [7] Performance Evaluation of Methylation-Specific Real-time PCR (MSP) Assay for the Detection of O (6)-methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation in Glioblastoma Multiforme
    Barry, J.
    Talwalkar, S.
    [J]. JOURNAL OF MOLECULAR DIAGNOSTICS, 2018, 20 (06): : 1015 - 1015
  • [8] Variation of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma
    Parkinson, Jonathon F.
    Wheeler, Helen R.
    Clarkson, Adele
    McKenzie, Catriona A.
    Biggs, Michael T.
    Little, Nicholas S.
    Cook, Raymond J.
    Messina, Marinella
    Robinson, Bruce G.
    McDonald, Kerrie L.
    [J]. JOURNAL OF NEURO-ONCOLOGY, 2008, 87 (01) : 71 - 78
  • [9] The promoter methylation and expression of the O6-methylguanine-DNA methyltransferase gene in uterine sarcoma and carcinosarcoma
    Bujko, Mateusz
    Kowalewska, Magdalena
    Danska-Bidzinska, Anna
    Bakula-Zalewska, Elwira
    Siedecki, Janusz A.
    Bidzinski, Mariusz
    [J]. ONCOLOGY LETTERS, 2012, 4 (03) : 551 - 555
  • [10] The promoter methylation status of the DNA repair gene O6-methylguanine-DNA methyltransferase in ulcerative colitis
    Shunji Matsumura
    Naohide Oue
    Reiko Ito
    Hirofumi Nakayama
    Yasuhiko Kitadai
    Hiroshi Yokozaki
    Kazuaki Chayama
    Wataru Yasui
    [J]. Virchows Archiv, 2003, 443 : 518 - 523
12345