The gut microbiome, probiotics, bile acids axis, and human health

被引：48
|
作者：
Jones, Mitchell Lawrence
Tomaro-Duchesneau, Catherine
Prakash, Satya [1 ]
机构：
[1] McGill Univ, Fac Med, Dept Biomed Engn, Biomed Technol & Cell Therapy Res Lab, Montreal, PQ H3A 2B4, Canada
来源：
TRENDS IN MICROBIOLOGY | 2014年 / 22卷 / 06期
关键词：
REUTERI NCIMB 30242; METABOLISM;
D O I：
10.1016/j.tim.2014.04.010
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The human gut microbiome produces potent ligands to bile acid receptors, and probiotics could act as therapeutics of bile acid dysmetabolism. A recent study in Cell Reports demonstrates that probiotic VSL#3 affects bile acid deconjugation and excretion, as well as the gut-liver FXR-FGF15 axis.
引用
收藏
页码：306 / 308
页数：3
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