Two new monodesmosidic triterpene saponins from Gypsophila oldhamiana

被引：22
|
作者：
Luo, Jian-Guang
Kong, Ling-Yi
Takaya, Yoshiaki
Niwa, Masatake
机构：
[1] China Pharmaceut Univ, Dept Nat Med Chem, Nanjing 210009, Peoples R China
[2] Meijo Univ, Fac Pharm, Tempa Ku, Nagoya, Aichi 4688503, Japan
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2006年 / 54卷 / 08期
关键词：
Gypsophila oldhamiana; Caryophyllaceae; triterpenoid saponin; quillaic acid; vaccaric acid; immunologic activity;
D O I：
10.1248/cpb.54.1200
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new monodesmosidic triterpene saponins were isolated from the roots of Gypsophila oldhamiana (Caryophyllaceae). Their structures were elucidated on the basis of spectral data to be quillaic acid, alpha-L-arabinopyranosyl-(1 -> 4)-alpha-L-arabinopyranosyl-(1 -> 3)-[beta-D-Xylopyranosyl-(1 -> 4)-beta-L-rhamnopyranosyl-(1 -> 2)-beta-D-fucopyranosyl ester (1), and vaccaric acid, beta-D-glucopyranosyl-(1 -> 3)-[beta-D-xylopyranosyl-(1 -> 4)]-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-fucopyranosyl ester (2). Compound 1 showed a significant enhancement of granulocyte phagocytosis in vitro.
引用
收藏
页码：1200 / 1202
页数：3
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