Deep Brain Stimulation for Treatment of Refractory Epilepsy

被引：5

作者：

Fernandes de Oliveira, Tatiana von Hertwig ^{[1
]}

Cukiert, Arthur ^{[2
]}

机构：

[1] Hosp Univ Cajuru, Dept Neurosurg, Epilepsy Surg Program, Curitiba, Parana, Brazil

[2] Clin Cukiert, Dept Neurosurg, Epilepsy Surg Program, Sao Paulo, Brazil

来源：

NEUROLOGY INDIA | 2020年 / 68卷

关键词：

Deep brain stimulation; outcome; refractory epilepsy; CENTROMEDIAN THALAMIC NUCLEUS; HIPPOCAMPAL ELECTRICAL-STIMULATION; ANTERIOR NUCLEUS; SUBSTANTIA-NIGRA; CEREBELLAR STIMULATION; INTRACTABLE EPILEPSY; SUBTHALAMIC NUCLEUS; DOUBLE-BLIND; FREQUENCY STIMULATION; SEIZURE CONTROL;

D O I：

10.4103/0028-3886.302454

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Deep brain stimulation (DBS) has been used in the treatment of motor diseases with remarkable safety and efficacy, which abet the interest of its application in the management of other neurologic and psychiatric disorders such as epilepsy. Experimental data demonstrated that electric current could modulate distinct brain circuits and decrease the neuronal hypersynchronization seen in epileptic activity. The ability to carefully choose the most suitable anatomical target as well as to define the most reasonable stimulation parameters is highly dependable on the comprehension of the underlying mechanisms of action, which remain unclear. This review aimed to explore the relevant clinical data regarding the use of DBS in the treatment of refractory epilepsy.

引用

页码：268 / 277

页数：10

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