A novel simple and efficient bromination protocol for activated arenes

被引:23
|
作者
Tsoukala, Anna [1 ]
Liguori, Lucia [2 ]
Occhipinti, Giovanni [1 ]
Bjorsvika, Hans-Rene [1 ]
机构
[1] Univ Bergen, Dept Chem, N-5007 Bergen, Norway
[2] Fluens Synth AS, N-5008 Bergen, Norway
关键词
Bromination; Oxidation; Redox; Chemoselectivity; Green chemistry; Electrophilic substitution; ALKYL PHENYL ETHERS; AROMATIC-COMPOUNDS; POTASSIUM-BROMIDE; METAL BROMIDES; MONOBROMINATION; HALOGENATION; MECHANISM; OXONE(R); SOLVENT; HALIDE;
D O I
10.1016/j.tetlet.2008.12.016
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient, high yielding, and environmentally benign bromination using an alkali metal bromide as the bromine source is disclosed. Investigation of the protocol revealed that the method operates for activated arenes producing the corresponding monobrominated products in good to excellent yields. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:831 / 833
页数:3
相关论文
共 50 条
  • [1] PHOTOCHEMICAL BROMINATION OF SIMPLE ARENES
    BOLTON, R
    BHANGAR, MI
    WILLIAMS, GH
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1984, (05): : 893 - 896
  • [2] Butadiene Sulfone-catalyzed Monobromination of Arenes with NBS as the Bromination Source: A Simple, Mild, Efficient, and Chemoselective Protocol
    Sharma, Amit
    Rudrawar, Santosh
    Jadhav, Hemant R.
    LETTERS IN ORGANIC CHEMISTRY, 2024, 21 (02) : 201 - 208
  • [3] Simple bromination of activated arenes by IBX amide resin and tetraethyl-ammonium bromide
    Kim, DK
    Chung, WJ
    Lee, YS
    SYNLETT, 2005, (02) : 279 - 282
  • [4] Bromination of activated arenes by Oxone® and sodium bromide
    Lee, KJ
    Cho, HK
    Song, CE
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2002, 23 (05) : 773 - 775
  • [5] Efficient electrophilic cobromination of alkenes and bromination of activated arenes with bromodichloroisocyanuric acid under mild conditions
    de Almeida, Leonardo S.
    Esteves, Pierre M.
    de Mattos, Marcio C. S.
    SYNLETT, 2007, (11) : 1687 - 1690
  • [6] ULTRASOUND PROMOTED BROMINATION OF ACTIVATED ARENES WITH N-BROMOSUCCINIMIDE
    PAUL, V
    SUDALAI, A
    DANIEL, T
    SRINIVASAN, KV
    SYNTHETIC COMMUNICATIONS, 1995, 25 (16) : 2401 - 2405
  • [7] Scalable and efficient electrochemical bromination of arenes with Faradaic efficiencies surpassing 90%
    Zhang, Bing
    Liu, Wei
    Liu, Zhu
    Pei, Yuhou
    Li, Di
    Yang, Hongbin
    Qiu, Chuntian
    Fan, Yang
    Xu, Yinghua
    Ding, Jie
    Yu, Lei
    Liu, Bin
    Su, Chenliang
    NATURE COMMUNICATIONS, 2025, 16 (01)
  • [8] Bromination of deactivated aromatics: A simple and efficient method
    Rajesh, K.
    Somasundaram, M.
    Saiganesh, R.
    Balasubramanian, K. K.
    JOURNAL OF ORGANIC CHEMISTRY, 2007, 72 (15): : 5867 - 5869
  • [9] Efficient and Practical Oxidative Bromination and Iodination of Arenes and Heteroarenes with DMSO and Hydrogen Halide: A Mild Protocol for Late-Stage Functionalization
    Song, Song
    Sun, Xiang
    Li, Xinwei
    Yuan, Yizhi
    Jiao, Ning
    ORGANIC LETTERS, 2015, 17 (12) : 2886 - 2889
  • [10] Iodination of activated arenes using silfen: an improved protocol
    Tilve, TD
    Alexander, VM
    Khadilkar, BM
    TETRAHEDRON LETTERS, 2002, 43 (51) : 9457 - 9459