Flavonoid glycosides from Terminalia catappa L.

被引:63
|
作者
Lin, YL [1 ]
Kuo, YH
Shiao, MS
Chen, CC
Ou, JC
机构
[1] Natl Res Inst Chinese Med, Taipei 112, Taiwan
[2] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan
[3] Vet Gen Hosp, Dept Med Res & Educ, Taipei 112, Taiwan
关键词
Terminalia catappa L; Combretaceae; dried fallen leaves; flavone glucopyranosides; antioxidant;
D O I
10.1002/jccs.200000030
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Under the inhibition of Cu+2-induced LDL oxidation-guided fractionation, two new flavone glycosides with galloyl substitution were isolated from the dried fallen leaves of Terminalia catappa L. Their structures were established as apigenin 6-C-(2 "-O-galloyl)-beta-D-glucopyranoside (1) and apigenin 8-C-(2 "-O-galloyl)-beta-D-glucopyranoside (2), together with four known flavone glycosides, isovitexin, vitexin, isoorientin, and rutin, on the basis of spectroscopic method. Compounds 1 and 2 showed significant antioxidative effects. Their IC50 were 2.1 and 4.5 mu M, respectively.
引用
收藏
页码:253 / 256
页数:4
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