Magnolol induces cell death through PI3K/Akt mediated epigenetic modifications boosting targeted inhibition in BRAF and NRAS mutant melanoma

被引：0
|
作者：
Emran, A. [1 ,2 ]
Chowdhury, B. R. [2 ]
Hammerlindl, H. [2 ]
Ahmed, F. [3 ]
Haass, N. K. [3 ]
Schuehly, W. [4 ]
Schaider, H. [2 ]
机构：
[1] Univ Queensland, Woolloongabba, Qld, Australia
[2] Univ Queensland, Diamantina Inst, Dermatol Res Ctr, Woolloongabba, Qld, Australia
[3] Univ Queensland, Diamantina Inst, Translat Res Inst, Woolloongabba, Qld, Australia
[4] Karl Franzens Univ Graz, Inst Pharmaceut Sci, Dept Pharmacognosy, Graz, Austria
来源：
AUSTRALASIAN JOURNAL OF DERMATOLOGY | 2018年 / 59卷
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页码：25 / 25
页数：1
相关论文
共 50 条
  • [1] Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma
    Al Emran, Abdullah
    Chowdary, Brinda Reddy Chinna
    Ahmed, Farzana
    Hammerlindl, Heinz
    Huefner, Antje
    Haass, Nikolas K.
    Sehuehly, Wolfgang
    Schaider, Helmut
    CANCER MEDICINE, 2019, 8 (03): : 1186 - 1196
  • [2] Inhibition of Axl Promotes the Therapeutic Effect of Targeted Inhibition of the PI3K/Akt Pathway in NRAS Mutant Melanoma Cells
    Gao, Xuejun
    Xue, Dandan
    Cheng, Jingjing
    Zhang, Xin
    Cai, Xia
    JOURNAL OF ONCOLOGY, 2022, 2022
  • [3] Parthenolide Inhibits Cell Viability and Induces Apoptosis in Melanoma through Inhibition of PI3K/AKT Signaling
    Zhang, Lichao
    Zi, Shaoxia
    JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2022, 36 (06): : 1781 - 1788
  • [4] Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia
    Veronika Ecker
    Martina Stumpf
    Lisa Brandmeier
    Tanja Neumayer
    Lisa Pfeuffer
    Thomas Engleitner
    Ingo Ringshausen
    Nina Nelson
    Manfred Jücker
    Stefan Wanninger
    Thorsten Zenz
    Clemens Wendtner
    Katrin Manske
    Katja Steiger
    Roland Rad
    Markus Müschen
    Jürgen Ruland
    Maike Buchner
    Nature Communications, 12
  • [5] Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia
    Ecker, Veronika
    Stumpf, Martina
    Brandmeier, Lisa
    Neumayer, Tanja
    Pfeuffer, Lisa
    Engleitner, Thomas
    Ringshausen, Ingo
    Nelson, Nina
    Juecker, Manfred
    Wanninger, Stefan
    Zenz, Thorsten
    Wendtner, Clemens
    Manske, Katrin
    Steiger, Katja
    Rad, Roland
    Mueschen, Markus
    Ruland, Juergen
    Buchner, Maike
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [6] Combination of MEK and PI3K inhibition in BRAF wild-type and mutant melanoma
    Zhang, Yanping
    Peng, Guangyong
    Hsueh, Eddy C.
    CANCER RESEARCH, 2016, 76
  • [7] Coordinate autophagy and PI3K/Akt/mTOR pathway inhibition enhances cell death in melanoma
    Xie, Xiaoqi
    Mehnert, Janice M.
    White, Eileen P.
    CANCER RESEARCH, 2012, 72
  • [8] Oxymatrine induces nasopharyngeal cancer cell death through inhibition of PI3K/AKT and NF-κB pathways
    Ni, Zhili
    Yi, Jingmei
    MOLECULAR MEDICINE REPORTS, 2017, 16 (06) : 9701 - 9706
  • [9] Insulin induces drug resistance in melanoma through activation of the PI3K/Akt pathway
    Chi, Mengna
    Ye, Yan
    Zhang, Xu Dong
    Chen, Jiezhong
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2014, 8 : 255 - 262
  • [10] Epigenetic Silencing Mediated through Activated PI3K/AKT Signaling in Breast Cancer
    Zuo, Tao
    Liu, Ta-Ming
    Lan, Xun
    Weng, Yu-I
    Shen, Rulong
    Gu, Fei
    Huang, Yi-Wen
    Liyanarachchi, Sandya
    Deatherage, Daniel E.
    Hsu, Pei-Yin
    Taslim, Cenny
    Ramaswamy, Bhuvaneswari
    Shapiro, Charles L.
    Lin, Huey-Jen L.
    Cheng, Alfred S. L.
    Jin, Victor X.
    Huang, Tim H. -M.
    CANCER RESEARCH, 2011, 71 (05) : 1752 - 1762
12345