Synthesis of 2-amino-4-(2-ethoxybenzo[d][1,3]dioxol-5-yl)-4H-pyran-3-Carbonitrile Derivatives and Their Biological Evaluation

被引：14

作者：

Baitha, Amresh ^{[1
]}

Gopinathan, Ajay ^{[1
]}

Krishnan, Kartik ^{[1
]}

Dabholkar, Vijay V. ^{[1
]}

机构：

[1] Guru Nanak Coll, Dept Chem, Organ Res Lab, Bombay 400037, Maharashtra, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2018年 / 55卷 / 05期

关键词：

MULTICOMPONENT REACTIONS; CHEMISTRY;

D O I：

10.1002/jhet.3152

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new class of substituted 2-amino-4-(2-ethoxybenzo[d][1,3]dioxol-5-yl)-4H-pyran-3-carbonitrile derivatives catalyzed by Imidazole under mild reaction conditions has been developed. A variety of functionalized 2-amino-4-(2-ethoxybenzo[d][1,3]dioxol-5-yl)-4H-pyran-3-carbonitrile scaffolds were assembled in high yields by this catalytic protocol. The newly synthesized compounds have been characterized by IR, H-1 NMR, C-13 NMR, and mass spectral data. The compounds were then evaluated for antimicrobial activities.

引用

页码：1189 / 1192

页数：4

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