Synthesis, structural and conformational study of some amides derived from N-methylpiperazine

被引：17
|
作者：
Iriepa, I. [1 ]
Madrid, A. I.
Galvez, E.
Bellanato, J.
机构：
[1] Univ Alcala de Henares, Dept Quim Organ, Madrid, Spain
[2] CSIC, Inst Estructura Mat, E-28006 Madrid, Spain
来源：
JOURNAL OF MOLECULAR STRUCTURE | 2006年 / 787卷 / 1-3期
关键词：
N-methylpiperazine; amides; infrared spectroscopy; NMR spectroscopy; conformational analysis;
D O I：
10.1016/j.molstruc.2005.10.025
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Some amides (1-6) derived from N-methylpiperazine were synthesized and studied by IR, H-1 and C-13 NMR spectroscopy. In CDCl3 solution, at room temperature, a fast interconversion of the piperazine ring with the N-CH3 group in equatorial position can be proposed. alpha,beta-unsaturated compounds 4 and 5 adopt in liquid state and in solution (CCl4, CCl2=CCl2, CDCl3) both s-cis and s-trans conformations. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码：8 / 13
页数：6
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