A phase I first-in-human study of REGN910 (SAR307746), a fully human and selective angiopoietin-2 (Ang2) monoclonal antibody (MAb), in patients with advanced solid tumor malignancies.

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作者
Papadopoulos, Kyriakos P.
Sahebjam, Solmaz
Kelley, Robin Katie
Tolcher, Anthony W.
Razak, Albiruni R. A.
Patnaik, Amita
Bedard, Philippe L.
Arcos, Rebecca
Adriaens, Lieve
Brownstein, Carrie M.
Lowy, Israel
Gao, Bo
DiCioccio, A. Thomas
Trail, Pamela
Siu, Lillian L.
机构
[1] START Ctr Canc Care, San Antonio, TX USA
[2] Princess Margaret Hosp, Toronto, ON M4X 1K9, Canada
[3] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA
[4] South Texas Accelerated Res Therapeut LLC, San Antonio, TX USA
[5] Univ Toronto, Dept Med, Div Med Oncol & Hematol, Princess Margaret Canc Ctr,Univ Hlth Network, Toronto, ON, Canada
[6] Regeneron Pharmaceut Inc, Tarrytown, NY USA
[7] Princess Margaret Canc Ctr, Toronto, ON, Canada
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2517
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页数:1
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