ncRNA-Agents: A Multiagent System for Non-coding RNA Annotation

被引:0
|
作者
Arruda, Wosley [1 ]
Ralha, Celia G. [1 ]
Raiol, Taina [2 ]
Brigido, Marcelo M. [2 ]
Walter, Maria Emilia M. T. [1 ]
Stadler, Peter F. [3 ]
机构
[1] Univ Brasilia, Dept Comp Sci, BR-70910900 Brasilia, DF, Brazil
[2] Univ Brasilia, Inst Biol, Mol Biol Lab, Brasilia, DF, Brazil
[3] Univ Leipzig, Dept Comp Sci & Interdisciplinary Ctr Bioinformat, Leipzig, Germany
关键词
SECONDARY STRUCTURE; DATABASE; GENES; SEQUENCES; FAMILY; WORLD; CELLS;
D O I
暂无
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
In recent years, non-coding RNAs (ncRNAs) have been focus of intensive research. Since the characteristics and signals of ncRNAs are not entirely known, researchers use different computational tools together with their biological knowledge to predict potential ncRNAs. In this context, this work presents a multiagent system to annotate ncRNAs based on the output of different tools, using inference rules to simulate biologists' reasoning. Experiments with real data of fungi allowed to identify novel putative ncRNAs, which shows the usefulness of our approach.
引用
收藏
页码:136 / 147
页数:12
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