Stable insect cell cultures for recombinant protein production

被引：60

作者：

McCarroll, L ^{[1
]}

King, LA ^{[1
]}

机构：

[1] OXFORD BROOKES UNIV, SCH BIOL & MOL SCI, OXFORD OX3 0BP, ENGLAND

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1997年 / 8卷 / 05期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1016/S0958-1669(97)80034-1

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Insect cells are relatively cheap to maintain and are capable of producing accurately translated and correctly processed heterologous proteins. Recent research has focused on the development of improved expression vectors for continuous, high-level production of foreign proteins, including a number of membrane-targeted receptors, in Drosophila and lepidopteran insect cells. Mosquito cells have also been employed for studies on the control of vector-borne diseases, such as malaria.

引用

页码：590 / 594

页数：5

共 50 条

[1] EFFECT OF TEMPERATURE AND OXYGEN ON CELL-GROWTH AND RECOMBINANT PROTEIN-PRODUCTION IN INSECT CELL-CULTURES
REUVENY, S
KIM, YJ
KEMP, CW
SHILOACH, J
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1993, 38 (05) : 619 - 623
[2] Monitoring the progress of infection and recombinant protein production in insect cell cultures using intracellular ATP measurement
A. M. Olejnik
K. Czaczyk
R. Marecik
W. Grajek
T. Jankowski
Applied Microbiology and Biotechnology, 2004, 65 : 18 - 24
[3] RECOMBINANT PROTEIN-PRODUCTION IN INSECT CELL-CULTURES INFECTED WITH A TEMPERATURE-SENSITIVE BACULOVIRUS
WU, JY
KING, GA
DAUGULIS, AJ
FAULKNER, P
GOOSEN, MFA
CYTOTECHNOLOGY, 1992, 9 (1-3) : 141 - 147
[4] Use of on-line our measurements to monitor and improve insect cell cultures for recombinant protein production
Lecina, M
Casablancas, A
Soley, A
Vela, C
Espuña, E
De Gracia, J
Cairó, JJ
Gódia, F
Animal Cell Technology Meets Genomics, 2005, : 779 - 781
[5] Monitoring the progress of infection and recombinant protein production in insect cell cultures using intracellular ATP measurement
Olejnik, AM
Czaczyk, K
Marecik, R
Grajek, W
Jankowski, T
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2004, 65 (01) : 18 - 24
[6] CARBOHYDRATE-METABOLISM IN INSECT CELL-CULTURES DURING CELL-GROWTH AND RECOMBINANT PROTEIN-PRODUCTION
REUVENY, S
KEMP, CW
EPPSTEIN, L
SHILOACH, J
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES-SERIES, 1992, 665 : 230 - 237
[7] Screening of transformed insect cell lines for recombinant protein production
Keith, MB
Farrell, PJ
Iatrou, K
Behie, LA
BIOTECHNOLOGY PROGRESS, 1999, 15 (06) : 1046 - 1052
[8] TRANSFECTION OF SPODOPTERA FRUGIPERDA INSECT CELL AND PRODUCTION OF RECOMBINANT PROTEIN
Ustun Aytekin, Ozlem
PAMUKKALE UNIVERSITY JOURNAL OF ENGINEERING SCIENCES-PAMUKKALE UNIVERSITESI MUHENDISLIK BILIMLERI DERGISI, 2015, 21 (07): : 325 - 336
[9] PRODUCTION OF RECOMBINANT PROTEINS IN HIGH-DENSITY INSECT CELL-CULTURES
REUVENY, S
KIM, YJ
KEMP, CW
SHILOACH, J
BIOTECHNOLOGY AND BIOENGINEERING, 1993, 42 (02) : 235 - 239
[10] Production of a recombinant industrial protein using barley cell cultures
Ritala, A.
Wahlstrom, E. H.
Holkeri, H.
Hafren, A.
Makelainen, K.
Baez, J.
Makinen, K.
Nuutila, A. M.
PROTEIN EXPRESSION AND PURIFICATION, 2008, 59 (02) : 274 - 281

← 1 2 3 4 5 →