Population structure of Francisella tularensis

被引:36
|
作者
Nuebel, Ulrich
Reissbrodt, Rolf
Weller, Annette
Grunow, Roland
Porsch-Oezcueruemez, Mustafa
Tomaso, Herbert
Hofer, Erwin
Splettstoesser, Wolf
Finke, Ernst-Juergen
Tschaepe, Helmut
Witte, Wolfgang
机构
[1] Robert Koch Inst, D-38855 Wernigerode, Germany
[2] Bundeswehr Inst Microbiol, Munich, Germany
[3] Austrian Agcy Hlth & Food Safety, Modling, Austria
[4] Univ Hosp, Dept Microbiol, Rostock, Germany
关键词
D O I
10.1128/JB.01662-05
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We have sequenced fragments of five metabolic housekeeping genes and two genes encoding outer membrane proteins from 81 isolates of Francisella tularensis, representing all four subspecies. Phylogenetic clustering of gene sequences from F. tularensis subsp. tularensis and F. tularensis subsp. holarctica aligned well with subspecies affiliations. In contrast, F. tularensis subsp. novicida and F. tularensis subsp. mediasiatica were indicated to be phylogenetically incoherent taxa. Incongruent gene trees and mosaic structures of housekeeping genes provided evidence for genetic recombination in F. tularensis.
引用
收藏
页码:5319 / 5324
页数:6
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