GVHD therapy: the best-laid schemes...

被引：0

作者：

Komanduri, KV ^{[1
]}

Champlin, RE ^{[1
]}

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA

来源：

BLOOD | 2004年 / 104卷 / 05期

关键词：

D O I：

10.1182/blood-2004-06-2265

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Approaches to eliminate interleukin-2 receptor alpha (CD25(+)) cells have been widely pursued to selectively eliminate alloreactive cells that cause GVHD after allogeneic stem cell transplantation. In this issue, Lee and colleagues report paradoxical findings involving treatment with daclizumab, an anti-CD25 monoclonal antibody, possibly due to effects on CD4(+)CD25(+) immunoregulatory cells.

引用

页码：1240 / 1241

页数：2

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