Coronary Artery Calcium Score: the "Mammogram" of the Heart?

被引：14

作者：

Cainzos-Achirica, Miguel ^{[1
,2
,3
,4
,5
]}

Di Carlo, Philip A. ^{[6
]}

Handy, Catherine E. ^{[1
,7
]}

Quispe, Renato ^{[1
]}

Roura, Gerard ^{[2
,3
]}

Pinto, Xavier ^{[8
]}

Blumenthal, Roger S. ^{[1
]}

Comin-Colet, Josep ^{[2
,3
,9
]}

Corbella, Xavier ^{[3
,8
,10
,11
]}

Blaha, Michael J. ^{[1
,12
]}

机构：

[1] Johns Hopkins Med Inst, Johns Hopkins Ciccarone Ctr Prevent Cardiovasc Di, Baltimore, MD 21205 USA

[2] Bellvitge Univ Hosp, Dept Cardiol, 19th Floor,Feixa Llarga S-N, Barcelona 08907, Spain

[3] Bellvitge Biomed Res Inst IDIBELL, 19th Floor,Feixa Llarga S-N, Barcelona 08907, Spain

[4] Univ Int Catalunya, Sch Med & Med Sci, Barcelona, Spain

[5] RTI Hlth Solut, Pharmacoepidemiol & Risk Management, Barcelona, Spain

[6] Johns Hopkins Med Inst, Russell H Morgan Dept Radiol & Radiol Sci, Breast Imaging Div, 600 N Wolfe St, Baltimore, MD 21205 USA

[7] Johns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD 21205 USA

[8] Bellvitge Univ Hosp, Dept Internal Med, Cardiovasc Risk Unit, 7th Floor,Feixa Llarga S-N, Barcelona 08907, Spain

[9] Univ Barcelona, Dept Clin Sci, Barcelona, Spain

[10] Bellvitge Univ Hosp, Dept Internal Med, Barcelona, Spain

[11] Univ Int Catalunya, Sch Med & Hlth Sci, Integrated Hlth & Social Care, Barcelona, Spain

[12] Johns Hopkins Univ, Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA

来源：

CURRENT CARDIOLOGY REPORTS | 2018年 / 20卷 / 09期

关键词：

Atherosclerosis; Cardiovascular disease; Coronary artery calcium; Mammogram; Risk assessment; Screening; CARDIOVASCULAR-DISEASE; BREAST-CANCER; YOUNG-ADULTS; RISK-FACTORS; SUBCLINICAL ATHEROSCLEROSIS; COMPUTED-TOMOGRAPHY; FOLLOW-UP; EVENTS; METAANALYSIS; INDIVIDUALS;

D O I：

10.1007/s11886-018-1020-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To discuss the classic analogy of "coronary artery calcium (CAC) as a mammogram of the heart", by evaluating the conceptual strengths, weaknesses, opportunities, and threats of a potential cardiovascular disease (CVD) screening strategy using CAC in apparently healthy adults. CAC is typically used for further CVD risk assessment. CAC is also currently being used as a screening test in specific subgroups of individuals, particularly in some Asian countries. Although this has yielded valuable insights on the determinants and pathophysiology of CVD, whether this approach results in improved clinical outcomes compared to other assessment and management approaches is currently unclear. Although CAC and mammograms share a number of characteristics, there are also important conceptual differences. The evidence supporting CAC, which is a robust CVD risk assessment tool, for CVD screening purposes is currently very limited, and further research is needed.

引用

页数：10

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