Microtubule organization during in vitro development of rat oocytes

被引：0
|
作者：
Fan, HY [1 ]
Tong, C [1 ]
Li, SW [1 ]
Chen, DY [1 ]
Sun, QY [1 ]
机构：
[1] Chinese Acad Sci, Inst Zool, State Key Lab Reproduct Biol, Beijing 100080, Peoples R China
来源：
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS | 2002年 / 29卷 / 05期
关键词：
rat; oocyte; microtubule; meiosis;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Microtubule organization in developing rat oocytes were investigated through confocal microscopy. The inductive effects of some factors on microtubule modification were also studied. The results indicated that the meiotic cell cycle progression of rat oocyte is accompanied by extensive rearrangement of the microtubule network of the cell. Microtubule organization was modified by the treatment of oocytes with taxol, staurosporine, or okadaic acid. Rat oocytes released from the oviducts could undergo spontaneous parthenogenetic activation. They could also be induced to pseudo-cleave by cytochalasin B treatment. The microtubule configuration in rat oocytes undergoing spontaneous parthenogenetic activation or pseudo-cleavage was also observed.
引用
收藏
页码：708 / 713
页数：6
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