Evaluation of [18F]GE-180 PET imaging in relapsing-remitting multiple sclerosis patients: a first-in-human study

被引:0
|
作者
Trigg, W. [1 ]
Buckley, C. [1 ]
Heurling, K. [1 ]
Sherwin, P. [1 ]
Brooks, D. [1 ]
Sridharan, S. [2 ]
Hinz, R. [2 ]
Crouch, J. [3 ]
Lawlor, M. [3 ]
Amodeo, S. [3 ]
Paulseth, R. [3 ]
Gulenchyn, K. [3 ]
机构
[1] GE Healthcare, Imaging R&D, Amersham, England
[2] Univ Manchester, Manchester, Lancs, England
[3] St Josephs Hosp, Hamilton Hlth Sci, Hamilton, ON, Canada
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
P453
引用
收藏
页码:195 / 196
页数:2
相关论文
共 50 条
  • [1] Initial Evaluation of [18F]GE-180 PET Imaging in Relapsing-Remitting Multiple Sclerosis Patients
    Sridharan, S.
    Buckley, C.
    Trigg, W.
    Trigg, W.
    Heurling, K.
    Sherwin, P.
    Brooks, D.
    Crouch, J.
    Crouch, J.
    Lawler, M.
    Hinz, R.
    Paulseth, R.
    Amodeo, S.
    Gulenchyn, K.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2015, 42 : S276 - S277
  • [2] TSPO PET with [18F]GE-180 sensitively detects focal neuroinflammation in patients with relapsing-remitting multiple sclerosis
    Unterrainer, Marcus
    Mahler, C.
    Vomacka, L.
    Lindner, S.
    Havla, J.
    Brendel, M.
    Boening, G.
    Ertl-Wagner, B.
    Kuempfel, T.
    Milenkovic, V. M.
    Rupprecht, R.
    Kerschensteiner, M.
    Bartenstein, P.
    Albert, Nathalie L.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2018, 45 (08) : 1423 - 1431
  • [3] TSPO PET with [18F]GE-180 sensitively detects focal neuroinflammation in patients with relapsing–remitting multiple sclerosis
    Marcus Unterrainer
    C. Mahler
    L. Vomacka
    S. Lindner
    J. Havla
    M. Brendel
    G. Böning
    B. Ertl-Wagner
    T. Kümpfel
    V. M. Milenkovic
    R. Rupprecht
    M. Kerschensteiner
    P. Bartenstein
    Nathalie L. Albert
    [J]. European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45 : 1423 - 1431
  • [4] TSPO imaging using the novel PET ligand [18F]GE-180: quantification approaches in patients with multiple sclerosis
    Vomacka, Lena
    Albert, Nathalie Lisa
    Lindner, Simon
    Unterrainer, Marcus
    Mahler, Christoph
    Brendel, Matthias
    Ermoschkin, Larissa
    Gosewisch, Astrid
    Brunegraf, Anika
    Buckley, Christopher
    Kuempfel, Tania
    Rupprecht, Rainer
    Ziegler, Sibylle
    Kerschensteiner, Martin
    Bartenstein, Peter
    Boening, Guido
    [J]. EJNMMI RESEARCH, 2017, 7
  • [5] TSPO imaging using the novel PET ligand [18F]GE-180: quantification approaches in patients with multiple sclerosis
    Lena Vomacka
    Nathalie Lisa Albert
    Simon Lindner
    Marcus Unterrainer
    Christoph Mahler
    Matthias Brendel
    Larissa Ermoschkin
    Astrid Gosewisch
    Anika Brunegraf
    Christopher Buckley
    Tania Kümpfel
    Rainer Rupprecht
    Sibylle Ziegler
    Martin Kerschensteiner
    Peter Bartenstein
    Guido Böning
    [J]. EJNMMI Research, 7
  • [6] First quantification results for the new TSPO radioligand [18F]GE-180 in patients with multiple sclerosis
    Vomacka, L.
    Albert, N. L.
    Lindner, S.
    Unterrainer, M.
    Mahler, C.
    Brendel, M.
    Ermoschkin, L.
    Gosewisch, A.
    Brunegraf, A.
    Buckley, C.
    Trigg, W.
    Kuempfel, T.
    Rupprecht, R.
    Kerschensteiner, M.
    Bartenstein, P.
    Boening, G.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 44 : S420 - S421
  • [7] TSPO PET With 18F-GE-180 to Differentiate Variants of Multiple Sclerosis Relapsing-Remitting Multiple Sclerosis, Tumefactive Demyelination, and Balo's Concentric Sclerosis
    Voelk, Stefanie
    Unterrainer, Marcus
    Albert, Nathalie L.
    Havla, Joachim
    Gerdes, Lisa Ann
    Schumacher, Minh
    Brendel, Matthias
    Kaiser, Lena
    Adorjan, Kristina
    Rupprecht, Rainer
    Bartenstein, Peter
    Kuempfel, Tania
    Danek, Adrian
    [J]. CLINICAL NUCLEAR MEDICINE, 2020, 45 (10) : E447 - E448
  • [8] Quantification of the new TSPO ligand [18F]GE-180 in patients with multiple sclerosis - initial results
    Vomacka, Lena
    Albert, Nathalie
    Lindner, Simon
    Unterrainer, Marcus
    Mahler, Christoph
    Brendel, Matthias
    Ermoschkin, Larissa
    Gosewisch, Astrid
    Brunegraf, Anika
    Kmpfel, Tania
    Kerschensteiner, Martin
    Bartenstein, Peter
    Boening, Guido
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2017, 58
  • [9] UPTAKE OF [18F]GE-180 IN TSPO PET IS ASSOCIATED WITH SURVIVAL IN PATIENTS WITH RECURRENT GLIOMA
    Quach, Stefanie
    Holzgreve, Adrien
    Kaiser, Lena
    Unterrainer, Marcus
    Dekorsy, Franziska
    Nelwan, Debie V.
    Bartos, Laura
    Kirchleitner, Sabrina
    Weller, Jonathan
    Weidner, Lorraine
    Niyazi, Maximilian
    Ruf, Victoria
    Herms, Jochen
    Stoecklein, Sophia
    Wetzel, Christian
    Riemenschneider, Markus J.
    von Baumgarten, Louisa
    Thon, Niklas
    Brendel, Matthias
    Rupprecht, Rainer
    Bartenstein, Peter
    Tonn, Joerg-Christian
    Albert, Nathalie
    [J]. NEURO-ONCOLOGY, 2022, 24 : 167 - 168
  • [10] Evaluation of translocator protein as a target for imaging-activated microglia in multiple sclerosis and the development of a novel fluorine-18 labelled PET imaging agent for TSPO ([18F]GE-180)
    Trigg, W.
    Johansson, S.
    Fouladi, N.
    Jones, P. A.
    [J]. MULTIPLE SCLEROSIS JOURNAL, 2013, 19 (11) : 81 - 82