Highly enantio- and diastereoselective one-pot reactions in aqueous media:: Combined asymmetric Rh-catalyzed conjugate addition/metal-mediated allylation

被引：12

作者：

Kallstrom, Sara

Jagt, Richard B. C.

Sillanpaa, Reijo

Feringa, Ben L.

Minnaard, Adriaan J.

Leino, Reko

机构：

[1] Univ Groningen, Stratingh Inst, Dept Organ & Mol Inorgan Chem, NL-9747 AG Groningen, Netherlands

[2] Abo Akad Univ, Organ Chem Lab, SF-20500 Turku, Finland

[3] Univ Jyvaskyla, Dept Chem, SF-40351 Jyvaskyla, Finland

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 2006卷 / 17期

关键词：

asymmetric synthesis; conjugate addition; allylation; diastereoselectivity;

D O I：

10.1002/ejoc.200600309

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,3-Disubstituted, enantiopure cyclohexanols have been prepared in very high diastereoselectivities and good yields by a concise one-pot method combining the enantioselective rhodium-catalyzed conjugate addition of arylboronic acids with indium-mediated allylation into a highly efficient one-pot reaction in aqueous media. (c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006.

引用

页码：3826 / 3833

页数：8

共 6 条

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[6] Rh(I)-Catalyzed Transformation of Propargyl Vinyl Ethers into (E,Z)-Dienals: Stereoelectronic Role of trans Effect in a Metal-Mediated Pericyclic Process and a Shift from Homogeneous to Heterogeneous Catalysis During a One-Pot Reaction
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