Hematological Manifestations among Patients with Rheumatic Diseases

被引：23
|
作者：
Klein, Alina [1 ]
Molad, Yair [2 ,3 ]
机构：
[1] Beilinson Med Ctr, Rabin Med Ctr, Dept Internal Med C, IL-4941492 Petah Tiqwa, Israel
[2] Beilinson Med Ctr, Rabin Med Ctr, Inst Rheumatol, Petah Tiqwa, Israel
[3] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel
来源：
ACTA HAEMATOLOGICA | 2021年 / 144卷 / 04期
关键词：
Thrombocytopenia; Anemia; Leukopenia; Thrombosis; Thrombotic microangiopathy; Rheumatic diseases; Arthritis; Vasculitis; Systemic lupus erythematosus; Antiphospholipid syndrome; SYSTEMIC-LUPUS-ERYTHEMATOSUS; AUTOIMMUNE HEMOLYTIC-ANEMIA; VENOUS THROMBOEMBOLISM; THROMBOTIC MICROANGIOPATHY; CLASSIFICATION CRITERIA; IMMUNE CYTOPENIAS; BIOLOGICAL AGENTS; FELTYS-SYNDROME; NEUTROPENIA; RITUXIMAB;
D O I：
10.1159/000511759
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background: Rheumatic diseases have many hematological manifestations. Blood dyscrasias and other hematological abnormalities are sometimes the first sign of rheumatic disease. In addition, novel antirheumatic biological agents may cause cytopenias. Summary: The aim of this review was to discuss cytopenias caused by systemic lupus erythematosus and antirheumatic drugs, Felty's syndrome in rheumatoid arthritis, and autoimmune hemolytic anemia, thrombosis, and thrombotic microangiopathies related to rheumatological conditions such as catastrophic antiphospholipid syndrome and scleroderma renal crisis. Key Message: The differential diagnosis of various hematological disorders should include rheumatic autoimmune diseases among other causes of blood cell and hemostasis abnormalities. It is crucial that hematologists be aware of these presentations so that they are diagnosed and treated in a timely manner.
引用
收藏
页码：403 / 412
页数：10
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