Briarane diterpenes from two species of octocorals, Ellisella sp and Pteroeides sp.

被引：34
|
作者：
Tanaka, C
Yamamoto, Y
Otsuka, M
Tanaka, J
Ichiba, T
Marriott, G
Rachmat, R
Higa, T [1 ]
机构：
[1] Univ Ryukyus, Dept Chem Biol & Marine Sci, Nishihara, Okinawa 9030213, Japan
[2] Okinawa Ind Technol Ctr, Okinawa 9042234, Japan
[3] Univ Wisconsin, Dept Physiol, Madison, WI 53706 USA
[4] Res & Dev Ctr Oceanol, LIPI, Jakarta 11048, Indonesia
来源：
JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 08期
关键词：
D O I：
10.1021/np049923o
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Eight new briarane diterpenes (1-4, 7-10) have been isolated from two species of octocorals and the structures elucidated by spectroscopic analysis. Two diterpenes (2, 3) from the gorgonian Ellisella sp. inhibited cytokinesis, causing multinuclei formation on NBT-II cells, while a known briarane (12) from the sea pen Pteroeides sp. showed reversal of multidrug resistance.
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页码：1368 / 1373
页数：6
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