Prediction of Human Volume of Distribution Using in vivo, in vitro, and in silico Approaches

被引：9
|
作者：
Obach, R. Scott [1 ]
机构：
[1] Pfizer Global Res & Dev, Dept Pharmacokinet Pharmacodynam & Drug Metab, Groton Labs, Groton, CT USA
来源：
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 42 | 2007年 / 42卷
关键词：
D O I：
10.1016/S0065-7743(07)42030-9
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：469 / 488
页数：20
相关论文
共 50 条
  • [1] Evaluation of Prediction Accuracy for Volume of Distribution in Rat and Human Using In Vitro, In Vivo, PBPK and QSAR Methods
    Mathew, Shibin
    Tess, David
    Burchett, Woodrow
    Chang, George
    Woody, Nathaniel
    Keefer, Christopher
    Orozco, Christine
    Lin, Jian
    Jordan, Samantha
    Yamazaki, Shinji
    Jones, Rhys
    Di, Li
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 110 (04) : 1799 - 1823
  • [2] In Silico Prediction of Volume of Distribution in Human Using Linear and Nonlinear Models on a 669 Compound Data Set
    Berellini, Giuliano
    Springer, Clayton
    Waters, Nigel J.
    Lombardo, Franco
    JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (14) : 4488 - 4495
  • [3] Assessment of Thyroid Endocrine Disruption Effects of Parabens Using In Vivo, In Vitro, and In Silico Approaches
    Liang, Jiefeng
    Yang, Xiaoxi
    Liu, Qian S.
    Sun, Zhendong
    Ren, Zhihua
    Wang, Xiaoyun
    Zhang, Qing
    Ren, Xiaomin
    Liu, Xiuchang
    Zhou, Qunfang
    Jiang, Guibin
    ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 56 (01) : 460 - 469
  • [4] In vitro, in vivo and in silico models of drug distribution into the brain
    Summerfield, Scott G.
    Dong, Kelly C.
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2013, 40 (03) : 301 - 314
  • [5] In vitro, in vivo and in silico models of drug distribution into the brain
    Scott G. Summerfield
    Kelly C. Dong
    Journal of Pharmacokinetics and Pharmacodynamics, 2013, 40 : 301 - 314
  • [6] In vivo, in vitro, and in silico approaches to study induction of drug metabolism
    Meyer, UA
    Baader, M
    Fraser, D
    Gnerre, C
    Handschin, C
    Oscarson, M
    Podvinee, M
    DRUG METABOLISM REVIEWS, 2003, 35 : 9 - 9
  • [7] Study on Gluco-Regulatory Potential of Glimepiride Sulfonamide Using In silico, In Vitro and In Vivo Approaches
    Parmar, Hamendra Singh
    Bhinchar, Mahesh Kumar
    Bhatia, Muskan
    Chordia, Nikita
    Raval, Ishan
    Chauhan, Digvijay Singh
    Manivannan, E.
    Jatwa, Rameshwar
    Kumar, Anil
    CURRENT PHARMACEUTICAL DESIGN, 2014, 20 (32) : 5212 - 5217
  • [8] Appraisal of the Neuroprotective Potentials of Isoeugenol Using In-vitro, In-vivo and In-silico Approaches
    Alyami, Bandar A.
    Ahmad, Zeeshan
    Ghufran, Mehreen
    Mahnashi, Mater H.
    Sadiq, Abdul
    Ayaz, Muhammad
    CURRENT NEUROPHARMACOLOGY, 2025, 23 (03) : 317 - 328
  • [9] Screening of Multitarget Compounds against Acetaminophen Hepatic Toxicity Using In Silico, In Vitro, and In Vivo Approaches
    Ali, Muhammad
    Asghar, Esha
    Ali, Waqas
    Mustafa, Ghulam
    Ansari, Irfan Aamer
    Zia, Saadiya
    Ansari, Siddique Akber
    Khan, Sumaiya
    MOLECULES, 2024, 29 (02):
  • [10] IN SILICO PREDICTION OF IN VIVO EFFICACY OF SMALL MOLECULES ON MYCOBACTERIUM TUBERCULOSIS USING MACHINE LEARNING APPROACHES
    Gunturi, Sitarama
    Ramamurthi, Narayanan
    Vadagam, Pratyusha
    DRUG METABOLISM REVIEWS, 2015, 47 : 161 - 161
12345