Quality of Life in People with Young-Onset Alzheimer's Dementia and Frontotemporal Dementia

被引：17
|
作者：
Hvidsten, Lara [1 ,2 ]
Engedal, Knut [1 ,3 ]
Selbaek, Geir [1 ,4 ,5 ]
Wyller, Torgeir Bruun [5 ,6 ]
Bruvik, Froydis [7 ,8 ,9 ]
Kersten, Hege [1 ,10 ,11 ]
机构：
[1] Vestfold Hosp Trust, Norvvegian Natl Advisory Unit Ageing & Hlth, Tonsberg, Norway
[2] Vestfold Hosp Trust, Div Mental Hlth & Addict, Tonsberg, Norway
[3] Univ Oslo, Inst Clin Med, Oslo, Norway
[4] Innlandet Hosp Trust, Ctr Old Age Psychiat Res, Ottestad, Norway
[5] Univ Oslo, Fac Med, Oslo, Norway
[6] Oslo Univ Hosp, Dept Geriatr Med, Oslo, Norway
[7] Haraldsplass Deaconess Hosp, Bergen, Norway
[8] Univ Bergen, Ctr Elderly & Nursing Home Med, Bergen, Norway
[9] Dign Ctr, Bergen, Norway
[10] Univ Oslo, Sch Pharm, Pharmaceut Biosci, Oslo, Norway
[11] Telemark Hosp Trust, Dept Res & Dev, Skien, Norway
来源：
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS | 2018年 / 45卷 / 1-2期
关键词：
Young-onset dementia; Alzheimer's disease; Frontotemporal dementia; Quality of life; DISEASE-SPECIFIC MEASURES; NURSING-HOME RESIDENTS; NEUROPSYCHIATRIC SYMPTOMS; CARE; CAREGIVERS; SCALE; PERSPECTIVES; DEPRESSION; MILD; LONG;
D O I：
10.1159/000487263
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Aims: The aims of this study were to compare quality of life (QOL) in people with young-onset Alzheimer's (AD) and frontotemporal (FTD) dementia, explore variables associated with QOL, and compare QOL in young-onset dementia (YOD) and late-onset dementia (LOD). Methods: Cross-sectional data from a Nordic multicenter study of 50 community-dwelling participants with AD and 38 with FTD were included. A comparison group consisted of 100 people with LOD. QOL was measured using self-reported Euro-QOL 5-Dimension and the proxy version of Quality of Life in Alzheimer's Disease (QOL-AD) questionnaire. Neuropsychiatric symptoms and needs were assessed using the Cornell Scale for Depression in Dementia (CSDD), Neuropsychiatric Inventory (NPI), and Camberwell Assessment of Needs in the Elderly. Multiple linear regression and multilevel modeling was used to determine variables associated with QOL. Results: We found no differences between the two YOD groups in QOL. The variables associated with QOL were scores on the CSDD, NPI, and unmet needs. The proxy QOL-AD score in YOD was significantly higher compared to LOD (median 36.0 [IQR 10.0] vs. 33.0 [IQR 9.0]). Conclusion: The QOL in Nordic people with YOD was better compared to people with LOD. Our results show depressive symptoms to be associated with QOL irrespective of age and diagnosis. (C) 2018 S. Karger AG, Basel
引用
收藏
页码：91 / 104
页数：14
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