Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight

被引:582
|
作者
Lang, T
LeBlanc, A
Evans, H
Lu, Y
Genant, H
Yu, A
机构
[1] Univ Calif San Francisco, Dept Radiol, San Francisco, CA 94143 USA
[2] Baylor Coll Med, Dept Med, Houston, TX 77030 USA
[3] Univ Space Res Assoc, Life Sci Div, Houston, TX USA
[4] Wyle Labs, Houston, TX USA
关键词
spaceflight; bone QCT; bone densitometry; osteoporosis; mechanical loading;
D O I
10.1359/JBMR.040307
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We measured cortical and trabecular bone loss using QCT of the spine and hip in 14 crewmembers making 4- to 6-month flights on the International Space Station. There was no compartment-specific loss of bone in the spine. Cortical bone mineral loss in the hip occurred primarily by endocortical thinning.
引用
收藏
页码:1006 / 1012
页数:7
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