Silver-Mediated Radical Aryltrifluoromethylthiolaton of Activated Alkenes

被引：208
|
作者：
Yin, Feng [1 ]
Wang, Xi-Sheng [1 ]
机构：
[1] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China
来源：
ORGANIC LETTERS | 2014年 / 16卷 / 04期
基金：
美国国家科学基金会;
关键词：
ARYL FLUOROALKYL SULFIDES; ALPHA-FLUORINATED ETHERS; TRIFLUOROMETHANESULFENYL CHLORIDE; NUCLEOPHILIC TRIFLUOROMETHYLTHIOLATION; ELECTROPHILIC TRIFLUOROMETHANESULFANYLATION; OXIDATIVE TRIFLUOROMETHYLTHIOLATION; CATALYZED SYNTHESIS; BORONIC ACIDS; OXINDOLES; REAGENT;
D O I：
10.1021/ol403739w
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first example of silver-mediated oxidative aryltrifluoromethylthiolation of activated alkenes to produce valuable trifluoromethylthiole-containing oxindoles was developed. Mechanistic investigations indicated that this novel transformation proceeded through a unique F3CS center dot radical addition path, thus providing a practical and easy-handling method to generate a F3CS center dot radical in the laboratory.
引用
收藏
页码：1128 / 1131
页数：4
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