Biomimetic polyesters and their role in ion transport across cell membranes

被引：0

作者：

Jedlinski, Z ^{[1
]}

Kurcok, P ^{[1
]}

Adamus, G ^{[1
]}

Juzwa, M ^{[1
]}

机构：

[1] Polish Acad Sci, Ctr Polymer Chem, PL-41800 Zabrze, Poland

来源：

ACTA BIOCHIMICA POLONICA | 2000年 / 47卷 / 01期

关键词：

biomimetic poly-(R)-3-hydroxybutanoate; supramolecular alkali metal catalysts; ion transport through phospholipid bilayer membranes;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Syntheses of biomimetic low-molecular weight poly-(R)-3-hydroxybutanoate mediated by three types of supramolecular catalysts are presented. The utility of these synthetic polyesters for preparation of artificial channels in phospholipid bilayers capable of sodium and calcium ion transport across cell membranes, is discussed. Further studies on possible applications of these bio-polymers for manufacturing drugs of prolonged activity are under way.

引用

页码：79 / 85

页数：7

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