Extracellular Remodeling by Lysosomes: An Inside-Out Mechanism of Spine Plasticity

被引：1
|
作者：
Evans, Paul R. [1 ]
Yasuda, Ryohei [1 ]
机构：
[1] Max Planck Florida Inst Neurosci, Jupiter, FL 33458 USA
来源：
NEURON | 2017年 / 93卷 / 01期
关键词：
RELEASE; NAADP;
D O I：
10.1016/j.neuron.2016.12.025
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
In this issue of Neuron, Padamsey et al. (2017) demonstrate that neuronal activity triggers lysosomal fusion with the plasma membrane in dendrites. Quite unexpectedly, the lysosomes release signaling molecules that induce extracellular matrix remodeling to support long-lasting dendritic spine plasticity.
引用
收藏
页码：6 / 8
页数：3
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