A novel and efficient total synthesis of (±)-physostigmine

被引:29
|
作者
Kulkarni, Mukund G. [1 ]
Dhondge, Attrimuni P. [1 ]
Borhade, Ajit S. [1 ]
Gaikwad, Dnyaneshwar D. [1 ]
Chavhan, Sanjay W. [1 ]
Shaikh, Yunnus B. [1 ]
Ningdale, Vijay B. [1 ]
Desai, Mayur P. [1 ]
Birhade, Deekshaputra R. [1 ]
Shinde, Mahadev P. [1 ]
机构
[1] Univ Pune, Dept Chem, Pune 411007, Maharashtra, India
关键词
CATALYTIC ASYMMETRIC-SYNTHESIS; QUATERNARY CARBON CENTERS; INTRAMOLECULAR HECK REACTIONS; FORMAL TOTAL-SYNTHESIS; PRACTICAL TOTAL-SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; NUCLEOPHILIC-SUBSTITUTION; ABSOLUTE-CONFIGURATION; CALABAR ALKALOIDS; INDOLE SERIES;
D O I
10.1016/j.tetlet.2009.03.012
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Application of the Wittig olefination-Claisen rearrangement protocol for the total synthesis of (+/-)-physostigmine. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2411 / 2413
页数:3
相关论文
共 50 条
  • [1] A TOTAL SYNTHESIS OF (-)-PHYSOSTIGMINE
    NODE, M
    ITOH, A
    MASAKI, Y
    FUJI, K
    HETEROCYCLES, 1991, 32 (09) : 1705 - 1707
  • [2] FORMAL TOTAL SYNTHESIS OF (-)-PHYSOSTIGMINE
    Asakawa, Kaori
    Noguchi, Naoyoshi
    Nakada, Masahisa
    HETEROCYCLES, 2008, 76 (01) : 183 - 190
  • [3] A CHIRAL TOTAL SYNTHESIS OF (-)-PHYSOSTIGMINE
    NODE, M
    HAO, X
    FUJI, K
    CHEMISTRY LETTERS, 1991, (01) : 57 - 60
  • [4] Efficient formal total synthesis of physostigmine and physovenine:: Conformational analysis of key intermediates
    Morales-Ríos, MS
    Santos-Sánchez, NF
    Joseph-Nathan, P
    JOURNAL OF NATURAL PRODUCTS, 2002, 65 (02): : 136 - 141
  • [5] NOVEL SYNTHESIS OF THE (+/-)-PHYSOSTIGMINE FRAMEWORK
    MORALESRIOS, MS
    BUCIO, MA
    JOSEPHNATHAN, P
    TETRAHEDRON LETTERS, 1994, 35 (06) : 881 - 882
  • [6] A novel and efficient total synthesis of shikonin
    Wang, Rubing
    Guo, Hui
    Cui, Jiahua
    Li, Shaoshun
    TETRAHEDRON LETTERS, 2012, 53 (31) : 3977 - 3980
  • [7] A novel and efficient total synthesis of cephalotaxine
    Li, WDZ
    Wang, YQ
    ORGANIC LETTERS, 2003, 5 (16) : 2931 - 2934
  • [8] Total synthesis of strictamine: a tutorial for novel and efficient synthesis
    Wang, Chao
    Zhang, Shiju
    Wang, Yan
    Huang, Sha-Hua
    Hong, Ran
    ORGANIC CHEMISTRY FRONTIERS, 2018, 5 (03): : 447 - 452
  • [9] Novel synthesis of physovenine and physostigmine analogs
    Wang, C. H.
    Alluri, S.
    Nikogosyan, G.
    DeCarlo, C.
    Monteiro, C.
    Mabagos, G.
    Feng, H. H.
    White, A. R.
    Bartolini, M.
    Andrisano, V.
    Zhang, L. K.
    Ganguly, A. K.
    TETRAHEDRON LETTERS, 2016, 57 (27-28) : 3046 - 3049