Age-Specific Incidence of Influenza A Responds to Change in Virus Subtype Dominance

被引：7
|
作者：
Gagnon, Alain [1 ,2 ]
Acosta, Enrique [1 ,3 ]
Miller, Matthew S. [4 ]
机构：
[1] Univ Montreal, Dept Demog, Montreal, PQ, Canada
[2] Ctr Rech Sante Publ, Montreal, PQ, Canada
[3] Max Planck Inst Demog Res, Rostock, Germany
[4] McMaster Univ, McMaster Immunol Res Ctr, Michael G DeGroote Inst Infect Dis Res, Dept Biochem & Biomed Sci, Hamilton, ON, Canada
来源：
CLINICAL INFECTIOUS DISEASES | 2020年 / 71卷 / 07期
基金：
欧洲研究理事会; 加拿大健康研究院;
关键词：
influenza incidence; antigenic imprinting; cohort effect; age-specific analysis;
D O I：
10.1093/cid/ciaa075
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
When H3N2 replaced H1N1 as the dominant influenza A subtype during the 2018-2019 season, the pattern of age-specific incidence shifted due to the lingering effects of antigenic imprinting. The characteristic shape that imprinting leaves on influenza susceptibility could foster important advances in understanding and predicting the epidemiology of influenza.
引用
收藏
页码：E195 / E198
页数：4
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