Three novel triterpenoid saponins from Lysimachia capillipes and their cytotoxic activities

被引：33
|
作者：
Tian, JK [1 ]
Xu, LZ
Zou, ZM
Yang, SL
机构：
[1] Zhejiang Univ, Dept Chinese Med Sci & Engn, Hangzhou 310028, Peoples R China
[2] Chinese Acad Med Sci, Inst Med Plants Dev, Beijing 100094, Peoples R China
[3] Peking Union Med Coll, Beijing 100094, Peoples R China
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2006年 / 54卷 / 04期
关键词：
Lysimachia capillipes; capilliposide A; capilliposide B; capilliposide C; triterpene; saponin;
D O I：
10.1248/cpb.54.567
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Three new saponins, capilliposide A (1), capilliposide B (2) and capilliposide C (3) were isolated from an ethanol extract of Lysimachia capillipes. Their structures were determined by 1D and 2D NMR (H-1-H-1 COSY, HMBC, HMQC, DEPT and TOCSY) techniques, MS, and hydrolysis. Capilliposide B showed significant cytotoxicity against human A-2780 cells.
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页码：567 / 569
页数：3
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