Treatment of Stage II-III Rectal Cancer Patients

被引:10
|
作者
Kim, Miranda B. [1 ]
Hong, Theodore S. [1 ]
Wo, Jennifer Y. [1 ]
机构
[1] Massachusetts Gen Hosp, Boston, MA 02114 USA
关键词
Radiation therapy; Node-positive rectal cancer; Preoperative chemotherapy; Postoperative chemotherapy; Rectal cancer; Colorectal cancer; POSTOPERATIVE ADJUVANT CHEMOTHERAPY; TOTAL MESORECTAL EXCISION; MEDIAN FOLLOW-UP; PREOPERATIVE RADIOTHERAPY; RADIATION-THERAPY; RANDOMIZED-TRIAL; LOCAL EXCISION; CARCINOMA; CHEMORADIOTHERAPY; FLUOROURACIL;
D O I
10.1007/s11912-013-0362-0
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The role and sequencing of radiotherapy in the management of T3-4 or node- positive rectal cancer has evolved over the last few decades. Given the significant local failure rate following surgery alone, both preoperative and postoperative chemotherapy and radiotherapy have been studied to decrease local and systemic failure and improve survival in these patients. This review discusses current indications and controversies for treatment of stage II-III rectal cancer patients.
引用
收藏
页数:9
相关论文
共 50 条
  • [1] Neoadjuvant Treatment Approaches for Stage II-III Rectal Cancer
    Nurkin, Steven
    JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2023, 21 (5.5): : 572 - 575
  • [2] Neoadyuvant radiochemotherapy for elder patients with stage II-III rectal cancer
    Gomez Caamano, A.
    Castro, E.
    Anido, U.
    Varela, A.
    Vidal, Y.
    Curiel, T.
    Fernandez, E.
    Areses, K.
    Calvo, P.
    Lopez, R.
    JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15)
  • [3] Xeloda and radiotherapy in preoperative patients with rectal cancer stage II-III
    Gonzalez-Flores, E.
    Jimenez, B.
    Gonzalez-Astorga, B.
    Conde-Herrero, V
    Sanchez, C.
    Luclue, R.
    Valdivia, J.
    Ballesteros, P.
    Irigoyen, A.
    Delgado, J.
    ANNALS OF ONCOLOGY, 2008, 19 : 70 - 70
  • [4] Treatment of Stage II–III Rectal Cancer Patients
    Miranda B. Kim
    Theodore S. Hong
    Jennifer Y. Wo
    Current Oncology Reports, 2014, 16
  • [5] Raltitrexed and radiotherapy as adjuvant treatment for stage II-III rectal cancer: A feasibility study
    Lupattelli, Marco
    Maranzano, Ernesto
    Bellavita, Rita
    Natalini, Giovanni
    Corgna, Enrichetta
    Rossetti, Riccardo
    Trippa, Fabio
    Mascioni, Francesca
    Sidoni, Angelo
    Anselmo, Paola
    Buzzi, Franco
    Brugia, Mauro
    Latini, Paolo
    TUMORI JOURNAL, 2005, 91 (06): : 498 - 504
  • [6] SURVIVAL AFTER NEOADJUVANT RADIOCHEMOTHERAPY FOR ELDER PATIENTS WITH STAGE II-III RECTAL CANCER
    Anido, U.
    Castro-Gomez, E.
    Gomez-Caamano, A.
    Areses Manrique, M. C.
    Varela-Pazos, A.
    Garcia, J.
    Fernandez-Fernandez, E.
    Peleteiro, P.
    Gallardo, E.
    Lopez, R.
    ANNALS OF ONCOLOGY, 2008, 19 : 143 - 143
  • [7] Raltitrexed and radiotherapy as adjuvant treatment for stage II-III rectal cancer: A phase II study.
    Draghini, L.
    Lupattelli, M.
    Bellavita, R.
    Maranzano, E.
    Beneventi, S.
    D'Ambrosio, M. S.
    Trippa, F.
    Aristei, C.
    RADIOTHERAPY AND ONCOLOGY, 2006, 81 : S240 - S241
  • [8] Racial and Socioeconomic Treatment Disparities in Adolescents and Young Adults with Stage II-III Rectal Cancer
    Lee, David Y.
    Teng, Annabelle
    Pedersen, Rose C.
    Tavangari, Farees R.
    Attaluri, Vikram
    McLemore, Elisabeth C.
    Stern, Stacey L.
    Bilchik, Anton J.
    Goldfarb, Melanie R.
    ANNALS OF SURGICAL ONCOLOGY, 2017, 24 (02) : 311 - 318
  • [9] LMR predicts outcome in patients after preoperative chemoradiotherapy for stage II-III rectal cancer
    Abe, Shinya
    Kawai, Kazushige
    Nozawa, Hiroaki
    Hata, Keisuke
    Kiyomatsu, Tomomichi
    Morikawa, Teppei
    Watanabe, Toshiaki
    JOURNAL OF SURGICAL RESEARCH, 2018, 222 : 122 - 131
  • [10] Chemoradiation with raltitrexed (Tomudex) in preoperative treatment of stage II-III resectable rectal cancer:: A phase II study
    Gambacorta, MA
    Valentini, V
    Morganti, AG
    Mantini, G
    Miccichè, F
    Ratto, C
    Di Miceli, D
    Rotondi, F
    Alfieri, S
    Doglietto, GB
    Vargas, JG
    De Paoli, A
    Rossi, C
    Cellini, N
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2004, 60 (01): : 130 - 138