Comprehensive Analysis of Red Blood Cell Distribution Width as a Preoperative Prognostic Predictor in Gastric Cancer

被引：31
|
作者：
Hirahara, Noriyuki [1 ]
Tajima, Yoshitsugu [1 ]
Fujii, Yusuke [1 ]
Kaji, Shunsuke [1 ]
Yamamoto, Tetsu [1 ]
Hyakudomi, Ryoji [1 ]
Taniura, Takahito [1 ]
Kawabata, Yasunari [1 ]
机构：
[1] Shimane Univ, Fac Med, Dept Digest & Gen Surg, 89-1 Enya Cho, Izumo, Shimane 6938501, Japan
来源：
ANTICANCER RESEARCH | 2019年 / 39卷 / 06期
关键词：
Gastric cancer; red blood cell distribution width; prognostic factor; MORTALITY; MARKERS; INTERLEUKIN-6; ESOPHAGECTOMY; INFLAMMATION;
D O I：
10.21873/anticanres.13448
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background/Aim: The aim of the current study was to investigate the impact of the preoperative red cell distribution width (RDW) value on the overall survival (OS) and cancer-specific survival (CSS) of gastric cancer patients. Patients and Methods: A total of 366 gastric cancer patients who underwent curative gastrectomy were retrospectively reviewed. Among them, RDW was evaluated in 165 non-elderly and 201 elderly patients. Results: Multivariate analysis revealed that pathological stage (pStage), RDW, and carcinoembryonic antigen (CEA), were independent prognostic factors of OS, while pStage and RDW were independent prognostic factors of CSS. In non-elderly patients, based on the multivariate analysis, pStage, adjuvant chemotherapy, and RDW were identified as independent prognostic factors of OS. In elderly patients, RDW was identified as independent prognostic factors of OS and CSS. Conclusion: Preoperative RDW is a promising independent prognostic factor in gastric cancer.
引用
收藏
页码：3121 / 3130
页数：10
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