Factors related to asymptomatic or severe COVID-19 infection

被引:6
|
作者
Perez-Campos Mayoral, Eduardo [1 ,5 ]
Teresa Hernandez-Huerta, Maria [2 ,5 ]
Perez-Campos Mayoral, Laura [1 ,5 ]
Alberto Matias-Cervantes, Carlos [2 ,5 ]
Mayoral-Andrade, Gabriel [1 ,5 ]
Laguna Barrios, Luis Angel [3 ,5 ]
Perez-Campos, Eduardo [3 ,4 ,5 ]
机构
[1] Univ Autonoma Benito Juarez Oaxaca, Fac Med & Cirugia, Ctr Invest Fac Med UNAM UABJO, Oaxaca 68020, Oaxaca, Mexico
[2] Univ Autonoma Benito Juarez Oaxaca, Fac Med & Cirugia, CONACyT, Oaxaca 68020, Oaxaca, Mexico
[3] Univ Autonoma Benito Juarez Oaxaca, Fac Med & Cirugia, Oaxaca 68020, Oaxaca, Mexico
[4] Tecnol Nacl Mexico IT Oaxaca, Oaxaca 68020, Oaxaca, Mexico
[5] Lab Patol Clin Eduardo Perez Ortega, Oaxaca 68000, Oaxaca, Mexico
关键词
Factors; Asymptomatic; COVID-19; infection; ACE2; Blood group; Mutation; Histocompatibility complex (MHC) class I; Androgen; 25-Hydroxyvitamin D (25(OH)D); SYSTEM;
D O I
10.1016/j.mehy.2020.110296
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The factors that may contribute to a COVID-19 patient remaining in the asymptomatic stage, or to the infection evolving into the more serious stages are examined. In particular, we refer to the TMPRSS2 expression profile, balance of androgen and estrogen, blood group-A and/or B, nonsynonymous mutations in ORF3, and proteins NS7b and NS8 in SARS-CoV-2. Also, we review other factors related to the susceptibility and pathogenicity of SARS-CoV-2.
引用
收藏
页数:4
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