antiplatelet;
aspirin;
herb-drug interactions;
traditional Chinese medicine;
PLATELET-ACTIVATING-FACTOR;
GINKGO-BILOBA;
ANTIPLATELET ACTIVITY;
PANAX-GINSENG;
SCUTELLARIAE-RADIX;
OLDER-ADULTS;
DOUBLE-BLIND;
FOOD SPICE;
AGGREGATION;
INHIBITION;
D O I:
10.11622/smedj.2018051
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Traditional Chinese medicine (TCM)-based herbal therapies have gained increasing popularity worldwide, raising concerns of its efficacy, safety profile and potential interactions with Western medications. Antithrombotic agents are among the most common prescription drugs involved in herb-drug interactions, and this article focused on aspirin, one of the most widely used antiplatelet agents worldwide. We discussed herbs that have potential interactions by exploring Western and TCM approaches to thrombotic events. Common TCM indications for these herbs were also highlighted, including possible scenarios of their concurrent usage with aspirin. With greater awareness and understanding of potential herb-drug interactions, TCM and Western physicians may collaborate more closely to identify, treat and, most importantly, prevent adverse drug events.
机构:
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical UniversityNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University
Ling Ye
Shicheng Fan
论文数: 0引用数: 0
h-index: 0
机构:
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical UniversityNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University
Shicheng Fan
Pengfei Zhao
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h-index: 0
机构:
Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences,Sun Yat-sen UniversityNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University
Pengfei Zhao
Chenghua Wu
论文数: 0引用数: 0
h-index: 0
机构:
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical UniversityNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University
Chenghua Wu
Menghua Liu
论文数: 0引用数: 0
h-index: 0
机构:
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical UniversityNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University
Menghua Liu
Shuang Hu
论文数: 0引用数: 0
h-index: 0
机构:
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical UniversityNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University
Shuang Hu
Peng Wang
论文数: 0引用数: 0
h-index: 0
机构:
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical UniversityNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University
Peng Wang
Hongyu Wang
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h-index: 0
机构:
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical UniversityNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University
Hongyu Wang
Huichang Bi
论文数: 0引用数: 0
h-index: 0
机构:
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical UniversityNMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University
机构:
Southern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R ChinaSouthern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Ye, Ling
Fan, Shicheng
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R ChinaSouthern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Fan, Shicheng
Zhao, Pengfei
论文数: 0引用数: 0
h-index: 0
机构:
Sun Yat sen Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Design & Evaluat, Guangzhou 510006, Peoples R ChinaSouthern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Zhao, Pengfei
Wu, Chenghua
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R ChinaSouthern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Wu, Chenghua
Liu, Menghua
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R ChinaSouthern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Liu, Menghua
Hu, Shuang
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R ChinaSouthern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Hu, Shuang
Wang, Peng
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R ChinaSouthern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Wang, Peng
Wang, Hongyu
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R ChinaSouthern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Wang, Hongyu
Bi, Huichang
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R ChinaSouthern Med Univ, Sch Pharmaceut Sci, NMPA Key Lab Res & Evaluat Drug Metab, Guangzhou 510515, Peoples R China
机构:
George Washington Univ, Sch Med & Hlth Sci, Dept Hlth Care Sci, Washington, DC 20037 USAGeorge Washington Univ, Sch Med & Hlth Sci, Dept Hlth Care Sci, Washington, DC 20037 USA