Bauhinia candicans stimulation of glucose uptake in isolated gastric glands of normal and diabetic rabbits

被引:6
|
作者
Fuentes, O. [1 ]
Alarcon, J. [1 ]
机构
[1] Univ Bio Bio, Fac Ciencias, Dept Ciencias Basicas, Chillan, Chile
关键词
Bahuinia candicans; glucose uptake; isolated gastric glands; hypoglycemic activity; diabetes;
D O I
10.1016/j.fitote.2006.03.006
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A butanol extract of dried leaves of Bahuinia candicans showed, in vitro, a stimulatory effect of glucose uptake in isolated gastric glands of normal and alloxan-diabetic rabbits. The extract (0.001-0.07 mg/mg protein) produced a dose-dependent effect and was similar to the effect of insulin (1-100 nM). These findings suggest that the extract contains compound(s) that efficiently increase glucose transport at the basolateral side of isolated gastric glands. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:271 / 275
页数:5
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