Differences in cytochrome P450 3A4 (CYP3A4) expression alone do not explain inter-individual variability in CYP3A-mediated hepatic testosterone 6β hydroxylase (TST6βOH) activity

被引：0
|
作者：
Barter, Z. E. [1 ]
Crewe, K. H. [1 ]
Harlow, J. R. [1 ]
Lei, Y. [1 ]
Tucker, G. T. [1 ]
Rostami-Hodjegan, A. [1 ]
机构：
[1] Univ Sheffield, Sheffield S10 2TN, S Yorkshire, England
来源：
DRUG METABOLISM REVIEWS | 2006年 / 38卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
129
引用
收藏
页码：98 / 98
页数：1
相关论文
共 50 条
  • [1] New fluorescent probes for Cytochrome P450 3A4 (CYP3A4)
    Chougnet, Antoinette
    JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2007, 12 (SUPPL 1): : S55 - S55
  • [2] Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates
    Dilmaghanian, S
    Gerber, JG
    Filler, SG
    Sanchez, A
    Gal, J
    CHIRALITY, 2004, 16 (02) : 79 - 85
  • [3] Assessment of electrocatalytic hydroxylase activity of cytochrome P450 3A4 (CYP3A4) by means of derivatization of 6β-hydroxycortisol by sulfuric acid for fluorimetric assay
    Kuzikov, Alexey
    Masamrekh, Rami
    Shkel, Tatsiana
    Strushkevich, Natallia
    Gilep, Andrei
    Usanov, Sergey
    Archakov, Alexander
    Shumyantseva, Victoria
    TALANTA, 2019, 196 : 231 - 236
  • [4] A Measurement Method for Cytochrome P450 3A4 (CYP3A4)-mediated Oxidation of Cholesterol in Lipid Membranes
    Shoji, Atsushi
    Miki, Haruka
    Kikkawa, Mikiko
    Yamamoto, Miyu
    Moriiwa, Yukiko
    Morioka, Kazuhiro
    Yanagida, Akio
    SENSORS AND MATERIALS, 2022, 34 (03) : 951 - 960
  • [5] Effects of cytochrome (CYP) p450 3A4 inducers on CYP2B6 catalytic activity.
    Faucette, S
    Lindley, C
    Hawke, R
    Shord, S
    Clarke, M
    LeCluyse, E
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2001, 69 (02) : P10 - P10
  • [6] A pilot evaluation of alfentanil-induced miosis as a noninvasive probe for hepatic cytochrome P450 3A4 (CYP3A4) activity in humans
    Phimmasone, S
    Kharasch, ED
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2001, 70 (06) : 505 - 517
  • [7] Impact of Inter-individual Variability in CYP1A2 and CYP3A4 Activity on Sunitinib Metabolism
    Jackson, Klarissa
    Burnham, Elizabeth
    Abouda, Arsany
    Vergne, Matthew
    FASEB JOURNAL, 2020, 34
  • [8] Metabolic activation and cytochrome P450 inhibition of piperlonguminine mediated by CYP3A4
    Chi, Yuqian
    Zhu, Xiaoliang
    Chen, Yaxuan
    Li, Xin
    Jiang, Ziyi
    Jian, Xiaoyang
    Lian, Mengyuan
    Wu, Xiaodi
    Wang, Lei
    Sun, Mengmeng
    Shi, Xiaowei
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 268
  • [9] Cytochrome P450 expression and regulation in CYP3A4/CYP2D6 double transgenic humanized mice
    Felmlee, Melanie A.
    Lon, Hoi-Kei
    Gonzalez, Frank J.
    Yu, Ai-Ming
    DRUG METABOLISM AND DISPOSITION, 2008, 36 (02) : 435 - 441
  • [10] Docking Study of Noscapine into the Activity Cavity of Cytochrome P450 (CYP) 3A4
    Liu, Wenhua
    Wang, Shaofeng
    LATIN AMERICAN JOURNAL OF PHARMACY, 2014, 33 (05): : 875 - 878
12345