High hopes for CB2 receptors in neurogenesis

被引：7
|
作者：
Downer, Eric J. [1 ]
机构：
[1] Natl Univ Ireland Univ Coll Cork, Dept Anat & Neurosci, Cork, Ireland
来源：
BRITISH JOURNAL OF PHARMACOLOGY | 2014年 / 171卷 / 06期
关键词：
cannabinoid; CB2 cannabinoid receptor; neural stem cells; neurogenesis; HIV-1; CANNABINOID RECEPTORS; CELL-PROLIFERATION; TRANSGENIC MICE; PHARMACOLOGY;
D O I：
10.1111/bph.12548
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
During life, new neurons are continually added to hippocampal circuitry, with evidence suggesting that these adult-born neurons are functionally linked to cognition and emotion. The mammalian brain contains actively dividing neural stem cells in discrete regions, including the subventricular zone of the lateral ventricles and the subgranular zone of the dentate gyrus. Once mature, these neurons integrate into neuronal networks, forming synaptic connections with interneurons, mossy cells and CA3 pyramidal cells Linked ArticleThis article is a commentary on Avraham etal., pp. 468-479 of volume 171 issue 2. To view this paper visit
引用
收藏
页码：1345 / 1346
页数：2
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