Modulation of insulin signaling in human skeletal muscle in response to exercise

被引：21
|
作者：
Kirwan, JP
Jing, M
机构：
[1] Case Western Reserve Univ, Sch Med, Metrohlth Med Ctr, Dept Reprod Biol, Cleveland, OH 44109 USA
[2] Case Western Reserve Univ, Sch Med, Metrohlth Med Ctr, Dept Nutr, Cleveland, OH 44109 USA
来源：
EXERCISE AND SPORT SCIENCES REVIEWS | 2002年 / 30卷 / 02期
关键词：
insulin sensitivity; signal transduction; exercise training; PI; 3-kinase; TNF-alpha;
D O I：
10.1097/00003677-200204000-00008
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
KIRWAN, J.P., and M. JING. Modulation of insulin signaling in human skeletal muscle in response to exercise. Exerc. Sport Sci. Rev., Vol. 30, No. 2, pp. 85-90, 2002. Exercise is widely recommended for the treatment of obesity, insulin resistance, and type II diabetes mellitus. Recent discoveries in the molecular and cellular regulation of insulin-mediated glucose metabolism in skeletal muscle have provided a deeper understanding of how exercise modulates insulin action.
引用
收藏
页码：85 / 90
页数：6
相关论文
共 50 条
  • [1] Effects of exercise and insulin on insulin signaling proteins in human skeletal muscle
    Koval, JA
    Maezono, K
    Patti, ME
    Pendergrass, M
    DeFronzo, RA
    Mandarino, LJ
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 1999, 31 (07): : 998 - 1004
  • [2] Insulin signaling and insulin sensitivity after exercise in human skeletal muscle
    Wojtaszewski, JFP
    Hansen, BF
    Gade, J
    Kiens, B
    Markuns, JF
    Goodyear, LJ
    Richter, EA
    [J]. DIABETES, 2000, 49 (03) : 325 - 331
  • [3] Insulin signaling in human skeletal muscle - Time course and effect of exercise
    Wojtaszewski, JFP
    Hansen, BF
    Kiens, B
    Richter, EA
    [J]. DIABETES, 1997, 46 (11) : 1775 - 1781
  • [4] Insulin signaling in human skeletal muscle: Time course and effect of exercise
    Wojtaszewski, J
    Hansen, B
    Kiens, B
    Richter, E
    [J]. DIABETES, 1997, 46 : 88 - 88
  • [5] Modulation of MicroRNAs During Exercise and Disease in Human Skeletal Muscle RESPONSE
    McCarthy, John J.
    [J]. EXERCISE AND SPORT SCIENCES REVIEWS, 2011, 39 (04): : 219 - 219
  • [6] Differential effects of exercise on insulin-signaling gene expression in human skeletal muscle
    Wadley, GD
    Tunstall, RJ
    Sanigorski, A
    Collier, GR
    Hargreaves, M
    Cameron-Smith, D
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 2001, 90 (02) : 436 - 440
  • [7] Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise
    Thong, FSL
    Derave, W
    Kiens, B
    Graham, TE
    Urso, B
    Wojtaszewski, JFP
    Hansen, BF
    Richter, EA
    [J]. DIABETES, 2002, 51 (03) : 583 - 590
  • [8] Effect of N-acetylcysteine infusion on exercise-induced modulation of insulin sensitivity and signaling pathways in human skeletal muscle
    Trewin, Adam J.
    Lundell, Leonidas S.
    Perry, Ben D.
    Patil, Kim Vikhe
    Chibalin, Alexander V.
    Levinger, Itamar
    McQuade, Leon R.
    Stepto, Nigel K.
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2015, 309 (04): : E388 - E397
  • [9] EXERCISE AND INSULIN-MEDIATED SIGNALING IN SKELETAL-MUSCLE
    GOODYEAR, LJ
    [J]. FASEB JOURNAL, 1995, 9 (04): : A977 - A977
  • [10] Exercise effects of muscle insulin signaling and action - Invited review: Exercise training-induced changes in insulin signaling in skeletal muscle
    Zierath, JR
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 2002, 93 (02) : 773 - 781
12345