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Terpenoids from Tripterygium wilfordii
被引:43
|作者:
Li, KH
[1
]
Duan, HQ
[1
]
Kawazoe, K
[1
]
Takaishi, Y
[1
]
机构:
[1] UNIV TOKUSHIMA,FAC PHARMACEUT SCI,TOKUSHIMA 770,JAPAN
关键词:
Tripterygium wilfordii;
celastraceae;
root barks;
triterpene;
diterpene;
wilforic acid;
triptobenzene;
D O I:
10.1016/S0031-9422(97)00048-4
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
The methanol extract of the dried root barks of Tripterygium wilfordii afforded three novel D:A friedooleanan and 24-norfriedoolean triterpenoids: 2,3-dihydroxy-24-nor-D:A-friedooleana-1,3,5(10)-triene-29-oic, 2 beta-hydroxy-3-oxo-24-nor-D:A-friedooleana-4-ene-29-oic acid and 2 alpha-hydroxy-3-oxo-D:A-friedooleana-29-oic acid named wilforic acid A, B and C, and two novel abietane diterpenoids: 11-hydroxy-14-methoxy-18(4 --> 3)-abeo-abieta-3,8,11,13-tetraene-18-oic acid and 14,19 beta-dihydroxy-18(4 --> 3)-abeo-abieta-3,8,11,13-tetraene-18,19-olide named triptobenzene H and I. Their structures were established on the basis of spectroscopic studies. (C) 1997 Elsevier Science Ltd.
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页码:791 / 796
页数:6
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