Terpenoids from Tripterygium wilfordii

被引:43
|
作者
Li, KH [1 ]
Duan, HQ [1 ]
Kawazoe, K [1 ]
Takaishi, Y [1 ]
机构
[1] UNIV TOKUSHIMA,FAC PHARMACEUT SCI,TOKUSHIMA 770,JAPAN
关键词
Tripterygium wilfordii; celastraceae; root barks; triterpene; diterpene; wilforic acid; triptobenzene;
D O I
10.1016/S0031-9422(97)00048-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The methanol extract of the dried root barks of Tripterygium wilfordii afforded three novel D:A friedooleanan and 24-norfriedoolean triterpenoids: 2,3-dihydroxy-24-nor-D:A-friedooleana-1,3,5(10)-triene-29-oic, 2 beta-hydroxy-3-oxo-24-nor-D:A-friedooleana-4-ene-29-oic acid and 2 alpha-hydroxy-3-oxo-D:A-friedooleana-29-oic acid named wilforic acid A, B and C, and two novel abietane diterpenoids: 11-hydroxy-14-methoxy-18(4 --> 3)-abeo-abieta-3,8,11,13-tetraene-18-oic acid and 14,19 beta-dihydroxy-18(4 --> 3)-abeo-abieta-3,8,11,13-tetraene-18,19-olide named triptobenzene H and I. Their structures were established on the basis of spectroscopic studies. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:791 / 796
页数:6
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