A PDA-DTC/Cu-MnO2 nanoplatform for MR imaging and multi-therapy for triple-negative breast cancer treatment

被引：17

作者：

Hu, Xiaochun ^{[1
]}

Lu, Yonglin ^{[1
]}

Zhao, Wenrong ^{[2
]}

Sun, Menglin ^{[2
]}

Li, Ruihao ^{[1
]}

Feng, Lei ^{[1
]}

Yao, Tianming ^{[1
]}

Dong, Chunyan ^{[2
]}

Shi, Shuo ^{[1
]}

机构：

[1] Tongji Univ, Shanghai Key Lab Chem Assessment & Sustainabil, Sch Chem Sci & Engn, Breast Canc Ctr,Shanghai East Hosp,Sch Med, Shanghai, Peoples R China

[2] Nanjing Med Univ, Shanghai East Hosp, Breast Canc Ctr, Shanghai 200120, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 34期

关键词：

CHEMOTHERAPY; DISULFIRAM;

D O I：

10.1039/d1cc00987g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, a multi-functional nanoplatform (PDA-DTC/Cu-MnO2) was established, which has been employed for MR imaging-guided multi-therapy (CDT, PTT and chemotherapy) for cancer treatment. The in vitro and in vivo results confirmed that the biocompatible nanoplatform could significantly induce tumor cell death and inhibit tumor growth.

引用

页码：4158 / 4161

页数：4

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