Pain severity and healthcare resource utilization in patients with osteoarthritis in the United States

被引:16
|
作者
Nalamachu, Sri [1 ]
Robinson, Rebecca L. [2 ]
Viktrup, Lars [3 ]
Cappelleri, Joseph C. [4 ]
Bushmakin, Andrew G. [4 ]
Tive, Leslie [5 ]
Mellor, Jennifer [6 ]
Hatchell, Niall [6 ]
Jackson, James [6 ]
机构
[1] Mid Amer PolyClin, Overland Pk, KS 66210 USA
[2] Eli Lilly & Co, Patient Outcomes & Real World Evidence, Indianapolis, IN 46285 USA
[3] Eli Lilly & Co, Lilly Biomed Core Team, Indianapolis, IN 46285 USA
[4] Pfizer Inc, Stat, Groton, CT 06340 USA
[5] Pfizer Inc, Med Affairs, New York, NY USA
[6] Adelphi Real World, Real World Res, Bollington, England
关键词
Osteoarthritis; healthcare resource utilization; pain severity; real-world clinical practice; caregiver burden; physical mobility; physician-rated; patient-reported;
D O I
10.1080/00325481.2020.1841988
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective To evaluate healthcare resource utilization (HCRU) by osteoarthritis (OA) pain severity. Methods Cross-sectional surveys of US physicians and their patients were conducted between February and May 2017. Using the Numeric Rating Scale, patients were classified by self-reported pain intensity in the last week into mild (0-3), moderate (4-6), and severe (7-10) cohorts. Parameters assessed included clinical characteristics, HCRU, and current caregiver support. Descriptive statistics were obtained, and analysis of variance and chi-square tests were performed. Results Patients (n = 841) were mostly female (60.9%) and white (77.8%), with mean age of 64.6 years. Patients reported mild (45.4%), moderate (35.9%), and severe (18.7%) OA pain. Mean number of affected joints varied by pain severity (range mild: 2.7 to severe: 3.6; p < 0.0001). Pain severity was associated with an increased number of physician-reported and patient-reported overall healthcare provider visits (HCPs; both p < 0.001). As pain increased, patients reported an increased need for mobility aids, accessibility modifications to homes, and help with daily activities due to functional disability. The number of imaging tests used to diagnose OA was similar across pain severity but varied when used for monitoring (X-rays: p p < 0.0447). Hospitalization rates for OA were low but were significantly associated with pain severity (mild: 4.9%; severe: 11.5%). Emergency department visits were infrequent but increasing pain severity was associated with more prior and planned surgeries. Conclusion Greater current pain was associated with more prior HCRU including imaging for monitoring progression, HCP visits including more specialty care, hospitalizations, surgery/planned surgery, and loss of independence due to functional disability. Yet rates of hospitalizations and X-ray use were still sizable even among patients with mild pain. These cross-sectional findings warrant longitudinal assessment to further elucidate the impact of pain on HCRU.
引用
收藏
页码:10 / 19
页数:10
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