Human herpesvirus 6 infection associated with anticonvulsant hypersensitivity syndrome and reactive haemophagocytic syndrome

被引:162
|
作者
Descamps, V
Bouscarat, F
Laglenne, S
Aslangul, E
Veber, B
Descamps, D
Saraux, JL
Grange, MJ
Grossin, M
Navratil, E
Crickx, B
Belaich, S
机构
[1] HOP BICHAT,CLIN REANIMAT MALAD INFECTIEUSES,F-75877 PARIS,FRANCE
[2] HOP BICHAT,SERV VIROL,F-75877 PARIS,FRANCE
[3] CTR HOSPITALIER EMILE ROUX,SERV MED INTERNE,EAUBONNE,FRANCE
[4] HOP BICHAT,HEMATOL LAB,F-75877 PARIS,FRANCE
[5] HOP BICHAT,SERV ANATOMOPATHOL,F-75877 PARIS,FRANCE
[6] HOP BEAUJON,SERV ANATOMOPATHOL,CLICHY,FRANCE
关键词
D O I
10.1111/j.1365-2133.1997.tb03795.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Viral infections are thought to play a part in some cutaneous drug reactions, Human herpesvirus 6 (HHV6), which is the agent of exanthema subitum (sixth disease), has never been implicated in a drug reaction. We report a patient with severe phenobarbital-induced anticonvulsant hypersensitivity syndrome in whom a fulminant haemophagocytic syndrome was associated with HHV6 infection. We discuss the possible role of HHV6 in this reactive condition.
引用
收藏
页码:605 / 608
页数:4
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