Responsive Direct Brain Stimulation for Epilepsy

被引：59
|
作者：
Morrell, Martha J. [1 ,2 ]
Halpern, Casey [3 ]
机构：
[1] NeuroPace Inc, Mountain View, CA 94043 USA
[2] Stanford Univ, Dept Neurol & Neurol Sci, Stanford, CA 94305 USA
[3] Stanford Univ, Dept Neurosurg, Stanford, CA 94305 USA
来源：
NEUROSURGERY CLINICS OF NORTH AMERICA | 2016年 / 27卷 / 01期
关键词：
Closed-loop; Responsive; Stimulation; Epilepsy; Intractable; Intracranial; Electrocorticogram; Neurostimulator; QUALITY-OF-LIFE; VAGUS NERVE-STIMULATION; TEMPORAL-LOBE EPILEPSY; LONG-TERM TREATMENT; ELECTRICAL-STIMULATION; THALAMIC-STIMULATION; DEEP; NEUROSTIMULATION; SEIZURES; NUCLEUS;
D O I：
10.1016/j.nec.2015.08.012
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Closed-loop, responsive direct brain stimulation provides a new treatment option for patients with refractory partial onset seizures who are not good candidates for potentially curative epilepsy surgery. The first responsive brain neurostimulator (RNS System, NeuroPace) provides stimulation directly to the seizure focus when abnormal electrocorticographic activity is detected. Seizure reductions of 44% at one year increase to 60 to 66% at years three to six of treatment. There is no negative impact on cognition and mood. Risks are similar to other implanted medical devices, and therapeutic stimulation is not perceived.
引用
收藏
页码：111 / +
页数：12
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