Role of miRNAs in the progression of malignant melanoma

被引：88
|
作者：
Mueller, D. W. [1 ]
Bosserhoff, A. K. [1 ]
机构：
[1] Univ Regensburg, Inst Pathol, D-93053 Regensburg, Germany
来源：
BRITISH JOURNAL OF CANCER | 2009年 / 101卷 / 04期
关键词：
miRNA; melanoma; microarray; MICRORNA EXPRESSION PROFILES; TRANSCRIPTION FACTOR; CELL LINES; C-ELEGANS; POSTTRANSCRIPTIONAL REGULATION; REGULATORY RNA; HUMAN CANCER; TARGETS; PATHWAY; METASTASIS;
D O I：
10.1038/sj.bjc.6605204
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Analysis of microRNA (miRNA) biogenesis and function is an area of research that started only recently but has subsequently accelerated tremendously. This is because of the impressive impact of miRNA-mediated gene regulation and the obvious potential of those tiny RNA molecules in future diagnostic and therapeutic applications. In this review, recent progress to reveal the role of miRNAs in the tumourigenesis of malignant melanoma, as well as future prospects of melanoma-related miRNA research, will be addressed. British Journal of Cancer (2009) 101, 551-556. doi: 10.1038/sj.bjc.6605204 www.bjcancer.com Published online 28 July 2009 (C) 2009 Cancer Research UK
引用
收藏
页码：551 / 556
页数：6
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